• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

腰椎手术后脑脊液漏的治疗新策略。

The New Strategy for the Treatment of Cerebrospinal Fluid Leak Following Lumbar Surgery.

作者信息

Ishimoto Yuyu, Kawakami Mamoru, Curtis Elizabeth, Cooper Cyrus, Moriguchi Nami, Nakao Shin-Ichi, Nakagawa Yukihiro

机构信息

Department of Orthopaedic Surgery, Kinan Hospital, Wakayama, Japan.

Spine Care Center, Wakayama Medical University Kihoku Hospital, Katsuragicho, Japan.

出版信息

Spine Surg Relat Res. 2019 Sep 20;4(1):95-98. doi: 10.22603/ssrr.2019-0037. eCollection 2020.

DOI:10.22603/ssrr.2019-0037
PMID:32039306
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7002059/
Abstract

INTRODUCTION

Cerebrospinal fluid (CSF) leak is a common complication of surgery involving the lumbar spine. However, although there are various therapeutic options for CSF leak, there is currently no optimal technique, and the choice of therapy often depends on the surgeon's cumulative experience. The aim of this study was to describe the successful treatment of CSF leakage using blood injection therapy along the drain removal tract.

TECHNICAL NOTE

We enrolled 7 consecutive patients who underwent lumbar surgery at our institute. The surgeries performed included decompression in two patients (one microendoscopic surgery), fusion in four, and an epidural cyst resection in one. After finding a CSF leak, we injected about 10 ml of blood from the patient into the drain tract. CSF leak did not recur after the blood injection in any of the seven patients. Following just one day of bed rest, the symptoms of intracranial hypotension disappeared with no instances of worsened symptoms of back pain, lower limb pain or fever.

CONCLUSIONS

We propose this route of blood injection therapy as a novel method for the treatment of CSF leak after lumbar surgery.

摘要

引言

脑脊液漏是腰椎手术常见的并发症。然而,尽管针对脑脊液漏有多种治疗选择,但目前尚无最佳技术,治疗方法的选择往往取决于外科医生的累积经验。本研究的目的是描述沿引流管拔除路径注射血液治疗脑脊液漏的成功案例。

技术说明

我们纳入了在我院接受腰椎手术的7例连续患者。手术包括2例减压手术(1例显微内镜手术)、4例融合手术和1例硬膜外囊肿切除术。发现脑脊液漏后,我们从患者体内抽取约10毫升血液注入引流管路径。7例患者注射血液后脑脊液漏均未复发。仅卧床休息一天后,颅内低压症状消失,未出现背痛、下肢疼痛或发热症状加重的情况。

结论

我们提出这种血液注射治疗途径作为腰椎手术后治疗脑脊液漏的一种新方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/328c/7002059/64167e9690c3/2432-261X-4-0095-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/328c/7002059/43bdafbafe63/2432-261X-4-0095-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/328c/7002059/64167e9690c3/2432-261X-4-0095-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/328c/7002059/43bdafbafe63/2432-261X-4-0095-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/328c/7002059/64167e9690c3/2432-261X-4-0095-g002.jpg

相似文献

1
The New Strategy for the Treatment of Cerebrospinal Fluid Leak Following Lumbar Surgery.腰椎手术后脑脊液漏的治疗新策略。
Spine Surg Relat Res. 2019 Sep 20;4(1):95-98. doi: 10.22603/ssrr.2019-0037. eCollection 2020.
2
A short review on a complication of lumbar spine surgery: CSF leak.腰椎手术并发症:脑脊液漏的简短综述。
Clin Neurol Neurosurg. 2015 Dec;139:248-51. doi: 10.1016/j.clineuro.2015.10.013. Epub 2015 Oct 23.
3
Oblique Intrathecal Injection in Lumbar Spine Surgery: A Technical Note.腰椎手术中斜角蛛网膜下腔注射:技术说明。
Can J Neurol Sci. 2017 Sep;44(5):514-517. doi: 10.1017/cjn.2017.45. Epub 2017 May 8.
4
Use of an External Ventricular Drain for Treatment of a Thoracolumbar Cerebrospinal Fluid Leak: A Case Report and Review of Literature.使用外部脑室引流治疗胸腰椎脑脊液漏:病例报告及文献综述
Cureus. 2022 Apr 12;14(4):e24066. doi: 10.7759/cureus.24066. eCollection 2022 Apr.
5
The awake endoscope-guided sealant technique with fibrin glue in the treatment of postoperative cerebrospinal fluid leak after extended transsphenoidal surgery: technical note.清醒状态下内镜引导使用纤维蛋白胶封堵技术治疗扩大经蝶手术后的脑脊液漏:技术说明
World Neurosurg. 2014 Sep-Oct;82(3-4):e479-85. doi: 10.1016/j.wneu.2013.01.017. Epub 2013 Jan 8.
6
Comparison of symptomatic cerebral spinal fluid leak between patients undergoing minimally invasive versus open lumbar foraminotomy, discectomy, or laminectomy.微创与开放腰椎椎间孔切开术、椎间盘切除术或椎板切除术患者症状性脑脊液漏的比较。
World Neurosurg. 2014 Mar-Apr;81(3-4):634-40. doi: 10.1016/j.wneu.2013.11.012. Epub 2013 Nov 13.
7
Cerebrospinal fluid outflow resistance as a diagnostic marker of spontaneous cerebrospinal fluid leakage.脑脊液流出阻力作为自发性脑脊液漏的诊断标志物。
J Neurosurg Spine. 2017 Aug;27(2):227-234. doi: 10.3171/2017.1.SPINE16548. Epub 2017 Jun 2.
8
The Cervical Spine as a Predominant Site of Cerebrospinal Fluid Leak: Preliminary Results Using the Overflow Leak Test.颈椎作为脑脊液漏的主要部位:使用溢出漏测试的初步结果。
World Neurosurg. 2020 Oct;142:e372-e377. doi: 10.1016/j.wneu.2020.07.017. Epub 2020 Jul 11.
9
Brain Herniation Secondary to Cerebrospinal Fluid Leak Following Elective Lumbar Spine Surgery.择期腰椎手术后脑脊液漏继发脑疝
Cureus. 2021 Dec 8;13(12):e20266. doi: 10.7759/cureus.20266. eCollection 2021 Dec.
10
Treatment Patterns and Health Care Resource Utilization of Iatrogenic Spinal Cerebrospinal Fluid Leaks in the United States.美国医源性脊髓脑脊液漏的治疗模式和医疗资源利用情况。
Clin Spine Surg. 2022 Nov 1;35(9):E725-E730. doi: 10.1097/BSD.0000000000001363. Epub 2022 Jul 14.

引用本文的文献

1
Treatment, Outcome, and Relapse of Spontaneous and Nonspontaneous Cerebrospinal Fluid Leak.自发性和非自发性脑脊液漏的治疗、结局及复发
Brain Sci. 2022 Mar 2;12(3):340. doi: 10.3390/brainsci12030340.

本文引用的文献

1
Epidural Blood Patch Performed for Severe Intracranial Hypotension Following Lumbar Cerebrospinal Fluid Drainage for Intracranial Aneurysm Surgery. Retrospective Series and Literature Review.颅内动脉瘤手术后腰椎脑脊液引流致严重颅内低压行硬膜外血贴治疗:回顾性系列研究与文献综述
J Cerebrovasc Endovasc Neurosurg. 2015 Dec;17(4):318-23. doi: 10.7461/jcen.2015.17.4.318. Epub 2015 Dec 31.
2
A short review on a complication of lumbar spine surgery: CSF leak.腰椎手术并发症:脑脊液漏的简短综述。
Clin Neurol Neurosurg. 2015 Dec;139:248-51. doi: 10.1016/j.clineuro.2015.10.013. Epub 2015 Oct 23.
3
Computed tomography-guided epidural patching of postoperative cerebrospinal fluid leaks.
计算机断层扫描引导下硬膜外修补术后脑脊液漏
J Neurosurg Spine. 2014 Nov;21(5):805-10. doi: 10.3171/2014.7.SPINE13965. Epub 2014 Aug 15.
4
Incidental durotomy during spine surgery: incidence, management and complications. A retrospective review.脊柱手术中偶然的硬脊膜切开术:发生率、处理和并发症。回顾性研究。
Injury. 2012 Apr;43(4):397-401. doi: 10.1016/j.injury.2010.12.014. Epub 2011 Jan 19.
5
Patch technique for repair of a dural tear in microendoscopic spinal surgery.微内镜脊柱手术中硬膜撕裂修补的补片技术
J Bone Joint Surg Br. 2008 Aug;90(8):1066-7. doi: 10.1302/0301-620X.90B8.20938.
6
Experimental assessment of the drainage capacity of small silastic chest drains.小型硅橡胶胸腔引流管引流能力的实验评估
Asian Cardiovasc Thorac Ann. 2006 Jun;14(3):223-6. doi: 10.1177/021849230601400311.
7
Prolonged Jackson-Pratt drainage in the management of lumbar cerebrospinal fluid leaks.延长杰克逊-普拉特引流在腰椎脑脊液漏管理中的应用
Surg Neurol. 2006 Apr;65(4):410-4, discussion 414-5. doi: 10.1016/j.surneu.2005.11.052.
8
CT-guided percutaneous fibrin glue therapy of cerebrospinal fluid leaks in the spine after surgery.
AJR Am J Roentgenol. 2000 Aug;175(2):443-6. doi: 10.2214/ajr.175.2.1750443.
9
Pseudomeningocele/CSF fistula in a patient with lumbar spinal implants treated with epidural blood patch and a brief course of closed subarachnoid drainage. A case report.硬膜外血贴联合短期蛛网膜下腔闭式引流治疗腰椎植入物患者的假性脑脊膜膨出/脑脊液瘘。病例报告。
Spine (Phila Pa 1976). 1996 Oct 1;21(19):2273-6. doi: 10.1097/00007632-199610010-00019.
10
Postoperative cerebrospinal fluid leaks of the lumbosacral spine: management with percutaneous fibrin glue.腰骶椎术后脑脊液漏:经皮应用纤维蛋白胶治疗
AJNR Am J Neuroradiol. 1996 Mar;17(3):495-500.