Hallsworth Kate, Adams Leon A
Institute of Cellular Medicine, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.
Liver Unit, The Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle, Upon Tyne, UK.
JHEP Rep. 2019 Nov 5;1(6):468-479. doi: 10.1016/j.jhepr.2019.10.008. eCollection 2019 Dec.
The development of non-alcoholic fatty liver disease is closely linked to lifestyle factors, namely excessive caloric intake coupled with reduced physical activity and exercise. This review aims to examine the evidence behind lifestyle change as a tool to improve hepatic steatosis and liver histology in patients with non-alcoholic fatty liver disease/non-alcoholic steatohepatitis. Furthermore, potential barriers to adopting lifestyle changes and strategies to overcome these barriers in the clinical setting are discussed.
非酒精性脂肪性肝病的发展与生活方式因素密切相关,即热量摄入过多,同时体力活动和锻炼减少。本综述旨在研究生活方式改变作为改善非酒精性脂肪性肝病/非酒精性脂肪性肝炎患者肝脂肪变性和肝脏组织学的一种手段背后的证据。此外,还讨论了在临床环境中采用生活方式改变的潜在障碍以及克服这些障碍的策略。