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年轻重度抑郁症患者行加速经颅磁刺激治疗中出现与经颅磁刺激相关的癫痫发作 1 例报告

A Case Report of Transcranial Magnetic Stimulation-Related Seizure in a Young Patient With Major Depressive Disorder Receiving Accelerated Transcranial Magnetic Stimulation.

机构信息

From the Résidence Ennesrine, La Soukra, Tunisia.

出版信息

J ECT. 2020 Sep;36(3):e31-e32. doi: 10.1097/YCT.0000000000000666.

DOI:10.1097/YCT.0000000000000666
PMID:32040022
Abstract

We report here the case of a transcranial magnetic stimulation (TMS)-related seizure observed after an accelerated TMS protocol in a young patient with major depressive disorder. The protocol consisted of delivering 5 sessions per day during 4 consecutive working days over the left dorsolateral prefrontal cortex. Stimulations were delivered at 20 Hz, with 40 trains, train duration of 1.9 seconds, intertrain interval of 12 seconds, and 1560 pulses per session. The event occurred during the third session (out of 5) of the second day (out of 4) into the 26th train (out of 40). Twelve days after the event, new sessions of stimulation (30 sessions of 1 Hz, 6 trains, train duration of 60 seconds, intertrain 30 seconds, 360 stimulations per session) followed by a maintenance protocol (1 session every 2 weeks) were proposed to the patient. This strategy allows us to achieve and maintain remission.

摘要

我们在此报告一例经颅磁刺激(TMS)相关癫痫发作的病例,该病例发生于一位接受强化 TMS 方案治疗的年轻重度抑郁症患者。该方案包括在连续 4 个工作日内每天进行 5 次治疗,刺激部位为左侧背外侧前额叶。刺激频率为 20 Hz,40 个序列,每个序列持续 1.9 秒,序列间间隔 12 秒,每个序列 1560 个脉冲。事件发生在第二天的第 26 个序列的第 3 个序列(共 40 个序列)中。事件发生 12 天后,向患者提出了新的刺激方案(1 Hz 共 30 个序列,每个序列 6 个序列,每个序列持续 60 秒,序列间间隔 30 秒,每个序列 360 个脉冲),随后进行维持方案(每 2 周 1 次)。该策略有助于达到和维持缓解。

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