Hamza Ameer, Gidley Paul W, Learned Kim O, Hanna Ehab Y, Bell Diana
Department of Pathology, University of Texas M. D. Anderson Cancer Center, Houston, Texas.
Department of Head and Neck Surgery, University of Texas M. D. Anderson Cancer Center, Houston, Texas.
Head Neck. 2020 Aug;42(8):1859-1873. doi: 10.1002/hed.26106. Epub 2020 Feb 10.
The temporomandibular joint (TMJ) harbors a myriad of pathologic alterations including arthritides and benign and malignant neoplasms.
Herein, we describe our institutional experience of some uncommon and unusual synovial pathologies of the TMJ along with a review of literature. We searched through the archives of department of pathology and institutional electronic medical record for specimens of TMJ between 1999 and 2019. Hematoxylin and eosin slides were reviewed and data (final diagnosis, age, gender, clinical presentation, tumor size, treatment modality, recurrence, and vital status) were collected.
A total of seven cases were identified including four cases of synovial chrondromatosis; and one case each of tenosynovial giant cell tumor, localized type, tenosynovial giant cell tumor, diffuse type, and synovial sarcoma.
The article emphasizes on the clinical, radiologic, pathologic, and molecular features of these uncommon entities. The differential diagnosis of each entity is also discussed. Current updates in the management are also reviewed.
颞下颌关节（TMJ）存在多种病理改变，包括关节炎以及良性和恶性肿瘤。
在此，我们描述了我们机构对颞下颌关节一些罕见和不寻常滑膜病变的经验，并对文献进行了综述。我们在病理科档案和机构电子病历中搜索了1999年至2019年期间的颞下颌关节标本。对苏木精和伊红染色切片进行了复查，并收集了数据（最终诊断、年龄、性别、临床表现、肿瘤大小、治疗方式、复发情况和生命状态）。
共确定了7例病例，包括4例滑膜软骨瘤病；腱鞘巨细胞瘤局限型、腱鞘巨细胞瘤弥漫型和滑膜肉瘤各1例。
本文强调了这些罕见实体的临床、放射学、病理学和分子特征。还讨论了每个实体的鉴别诊断。同时也回顾了当前治疗方法的进展。
