Division of Vascular and Endovascular Surgery, University of California San Francisco, San Francisco, Calif.
Department of Surgery, Zuckerberg San Francisco General Hospital, San Francisco, Calif.
J Vasc Surg. 2020 Feb;71(2):584-591.e1. doi: 10.1016/j.jvs.2019.03.083.
Regional anesthesia (RA)-induced vasodilation increases the proportion of patients with vein anatomy suitable for arteriovenous fistula (AVF) creation. The functional outcomes of AVFs created with veins initially small for size on preoperative duplex ultrasound mapping (≤2.4 mm) that are recruited under RA have not been clearly defined. We aimed to evaluate freedom from revision or thrombosis, time to first cannulation, and reintervention rates of AVFs created with veins recruited after induction of RA.
A prospectively maintained quality improvement database from a single institution was queried for patients who had dialysis access created under RA. We compared AVFs created according to the original surgical plan (preoperative minimum vein diameter >2.5 mm) with AVFs recruited with RA (preoperative minimum vein diameter ≤2.4 mm). End points included freedom from revision or thrombosis, time to first cannulation, and reintervention rates.
Between May 2014 and April 2018, there were 208 dialysis access cases performed under RA. Excluding grafts, revisions, patients with previous ipsilateral AVFs, and those without preoperative ultrasound vein mapping, 135 patients were included in our analysis. Induction of RA with intraoperative duplex ultrasound allowed a change in surgical plan in 55 of 135 (42%) patients (recruited with RA), including 31 patients originally scheduled for an arteriovenous graft (mean preoperative distal upper arm cephalic vein diameter of 1.8 mm [standard deviation, 0.2 mm]) who were converted to an AVF (12 brachiobasilic, 11 brachiocephalic, and 8 radiocephalic). The remaining patients in the group of AVFs recruited with RA included 13 scheduled for brachiobasilic configurations who were converted to brachiocephalic or radiocephalic AVFs and 11 scheduled for brachiocephalic AVFs who were converted to radiocephalic AVFs. Comparing AVFs created according to the original surgical plan vs AVFs recruited with RA, there were no differences in reintervention rates (48% vs 49%; P = .90) or functional outcomes at 6 months (60% vs 65% used on hemodialysis [P = .58] and 7% vs 2% primary failure [P = .19]).
In this series, RA increased the proportion of patients who underwent AVF creation without compromising functional outcomes. Routine use of RA in access surgery could have significant implications in meeting national guidelines for autogenous access in the prevalent hemodialysis population.
区域麻醉(RA)引起的血管扩张增加了适合动静脉瘘(AVF)创建的静脉解剖结构的患者比例。在术前双功能超声映射(≤2.4mm)上最初静脉尺寸较小(≤2.4mm)的静脉招募下创建的 AVF 的功能结果尚未明确界定。我们旨在评估在 RA 诱导下招募的静脉创建的 AVF 无修复或血栓形成、首次穿刺时间和再干预率。
从一个机构的前瞻性维护的质量改进数据库中查询了在 RA 下进行透析通路创建的患者。我们比较了根据原始手术计划(术前最小静脉直径>2.5mm)创建的 AVF 与在 RA 下招募的 AVF(术前最小静脉直径≤2.4mm)。终点包括无修复或血栓形成、首次穿刺时间和再干预率。
在 2014 年 5 月至 2018 年 4 月期间,共有 208 例透析通路在 RA 下进行。排除移植物、修订、同侧 AVF 患者以及没有术前超声静脉成像的患者后,我们的分析共纳入 135 例患者。术中双功能超声引导的 RA 允许改变 55 例(42%)患者的手术计划(在 RA 下招募),其中包括 31 例最初计划进行动静脉移植物(平均术前远侧上臂头静脉直径为 1.8mm[标准差,0.2mm])的患者,这些患者转换为 AVF(12 例臂骨基底,11 例臂头,8 例桡头)。RA 下招募的 AVF 组的其余患者包括 13 例预定为臂骨基底构型的患者,这些患者转换为臂头或桡头 AVF,以及 11 例预定为臂头 AVF 的患者,这些患者转换为桡头 AVF。比较根据原始手术计划创建的 AVF 与在 RA 下招募的 AVF,再干预率(48%与 49%;P=0.90)或 6 个月时的功能结果(60%与 65%用于血液透析[P=0.58]和 7%与 2%原发性失败[P=0.19])没有差异。
在本系列中,RA 增加了接受 AVF 治疗的患者比例,而不会影响功能结果。在通路手术中常规使用 RA 可能对满足流行血液透析人群中自体通路的国家指南具有重要意义。