Vaala W E, Clark E S, Orsini J A
Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, New Bolton Center, Kennett Square 19348.
J Am Vet Med Assoc. 1988 Nov 15;193(10):1273-7.
Gram-negative neonatal septicemia was diagnosed in a premature Standardbred colt. Clinical signs included lethargy, weakness, loss of suckle reflex, tachypnea, and injected mucous membranes. Sequelae included pneumonia, omphalophlebitis, septic arthritis, and osteomyelitis. Prepartum maternal uterine infection, premature delivery, abnormal parturition with premature fetal membrane separation, and failure of passive transfer of colostral immunoglobulins increased the foal's risk for developing sepsis. Treatment included administration of moxalactam disodium and cefadroxil. The clinical efficacy of cephalosporin antibiotics in the treatment of gram-negative sepsis is discussed.
一匹早产的标准赛马驹被诊断出患有革兰氏阴性菌新生儿败血症。临床症状包括嗜睡、虚弱、吸吮反射丧失、呼吸急促和黏膜充血。后遗症包括肺炎、脐静脉炎、败血症性关节炎和骨髓炎。产前母体子宫感染、早产、伴有胎膜过早分离的异常分娩以及初乳免疫球蛋白被动转移失败增加了马驹发生败血症的风险。治疗包括给予莫拉西林钠和头孢羟氨苄。讨论了头孢菌素类抗生素治疗革兰氏阴性菌败血症的临床疗效。
