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韩国2型糖尿病患者中胰岛素抵抗和心理性胰岛素抵抗的患病率。

The prevalence of insulin refusal and psychological insulin resistance among Korean patients with type 2 diabetes mellitus.

作者信息

Song Youngshin, Ku Bon Jeong, Cho Jeonghwa, Jun Younghee, Kim Bohyun, Nam Soohyun

机构信息

Chungnam National University College of Nursing, Daejeon, Republic of Korea.

Chungnam National University College of Medicine, Daejeon, Republic of Korea.

出版信息

Ann Transl Med. 2019 Dec;7(23):760. doi: 10.21037/atm.2019.11.77.

Abstract

BACKGROUND

This study investigated the prevalence of insulin refusal and compared the level of psychological insulin resistance (PIR) with the intention to accept insulin therapy among Korean patients with type 2 diabetes.

METHODS

Type 2 diabetes patients (n=1,209) were recruited from inner city outpatient diabetes clinics in 2016. Patient demographic, insulin recommendation, diabetes treatment type, intention to receive insulin therapy, and PIR information was collected using self-reports. The patients were divided into three groups: those who refused insulin therapy (n=184), those who accepted insulin therapy (n=331), and those not recommended for insulin therapy (n=694). Descriptive statistics were used to calculate the prevalence of insulin refusal; -tests and analyses of variance were used to compare demographics with PIR.

RESULTS

The insulin refusal rate was 35.7%. The duration of diabetes, numbers of diabetes-related complications, and glycated hemoglobin levels were significantly lower in the group not recommended for insulin therapy than refused and accepted insulin groups. The level of PIR in insulin refusal group was significantly lower among patients agreeing to receive insulin therapy within 3 months than among those refusing insulin therapy.

CONCLUSIONS

The prevalence of insulin refusal in Korea is not low, and people who refuse insulin therapy have high levels of PIR. Strategies to reduce PIR levels are needed.

摘要

背景

本研究调查了胰岛素拒绝的发生率,并比较了韩国2型糖尿病患者接受胰岛素治疗意愿的心理胰岛素抵抗(PIR)水平。

方法

2016年从市中心门诊糖尿病诊所招募了2型糖尿病患者(n = 1209)。通过自我报告收集患者的人口统计学信息、胰岛素推荐情况、糖尿病治疗类型、接受胰岛素治疗的意愿以及PIR信息。患者被分为三组:拒绝胰岛素治疗的患者(n = 184)、接受胰岛素治疗的患者(n = 331)以及未被推荐接受胰岛素治疗的患者(n = 694)。使用描述性统计来计算胰岛素拒绝的发生率;采用t检验和方差分析来比较人口统计学与PIR。

结果

胰岛素拒绝率为35.7%。未被推荐接受胰岛素治疗的组中,糖尿病病程、糖尿病相关并发症数量和糖化血红蛋白水平显著低于拒绝和接受胰岛素治疗的组。在同意在3个月内接受胰岛素治疗的患者中,胰岛素拒绝组的PIR水平显著低于拒绝胰岛素治疗的患者。

结论

韩国胰岛素拒绝的发生率不低,拒绝胰岛素治疗的人具有较高的PIR水平。需要采取降低PIR水平的策略。

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