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本文引用的文献

1
Dabigatran in patients with myocardial injury after non-cardiac surgery (MANAGE): an international, randomised, placebo-controlled trial.非心脏手术后心肌损伤患者的达比加群治疗(MANAGE):一项国际性、随机、安慰剂对照试验。
Lancet. 2018 Jun 9;391(10137):2325-2334. doi: 10.1016/S0140-6736(18)30832-8.
2
Troponin T monitoring to detect myocardial injury after noncardiac surgery: a cost-consequence analysis.肌钙蛋白T监测用于检测非心脏手术后心肌损伤:成本效益分析
Can J Surg. 2018 Jun;61(3):185-194. doi: 10.1503/cjs.010217.
3
Myocardial injury after noncardiac surgery-incidence and predictors from a prospective observational cohort study at an Indian tertiary care centre.非心脏手术后的心肌损伤——来自印度一家三级护理中心的前瞻性观察队列研究的发病率及预测因素
Medicine (Baltimore). 2018 May;97(19):e0402. doi: 10.1097/MD.0000000000010402.
4
Perioperative Myocardial Injury After Noncardiac Surgery: Incidence, Mortality, and Characterization.非心脏手术后围手术期心肌损伤:发生率、死亡率和特征。
Circulation. 2018 Mar 20;137(12):1221-1232. doi: 10.1161/CIRCULATIONAHA.117.030114. Epub 2017 Dec 4.
5
Canadian Cardiovascular Society Guidelines on Perioperative Cardiac Risk Assessment and Management for Patients Who Undergo Noncardiac Surgery.加拿大心血管学会关于非心脏手术患者围手术期心脏风险评估与管理的指南。
Can J Cardiol. 2017 Jan;33(1):17-32. doi: 10.1016/j.cjca.2016.09.008. Epub 2016 Oct 4.
6
Association between pre-operative statin use and major cardiovascular complications among patients undergoing non-cardiac surgery: the VISION study.非心脏手术患者术前使用他汀类药物与主要心血管并发症之间的关联:VISION研究
Eur Heart J. 2016 Jan 7;37(2):177-85. doi: 10.1093/eurheartj/ehv456. Epub 2015 Sep 1.
7
'Paradox' of troponin elevations after non-cardiac surgery.非心脏手术后肌钙蛋白升高的“悖论”
Br J Anaesth. 2015 Jun;114(6):863-5. doi: 10.1093/bja/aev068. Epub 2015 Mar 26.
8
Perioperative β blockade: guidelines do not reflect the problems with the evidence from the DECREASE trials.围手术期β受体阻滞剂:指南未反映DECREASE试验证据存在的问题。
BMJ. 2014 Aug 29;349:g5210. doi: 10.1136/bmj.g5210.
9
2014 ESC/ESA Guidelines on non-cardiac surgery: cardiovascular assessment and management: The Joint Task Force on non-cardiac surgery: cardiovascular assessment and management of the European Society of Cardiology (ESC) and the European Society of Anaesthesiology (ESA).2014年欧洲心脏病学会/欧洲麻醉学会非心脏手术心血管评估和管理指南:非心脏手术心血管评估和管理联合工作组,由欧洲心脏病学会(ESC)和欧洲麻醉学会(ESA)组成。
Eur Heart J. 2014 Sep 14;35(35):2383-431. doi: 10.1093/eurheartj/ehu282. Epub 2014 Aug 1.
10
2014 ACC/AHA guideline on perioperative cardiovascular evaluation and management of patients undergoing noncardiac surgery: executive summary: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines.2014年美国心脏病学会/美国心脏协会非心脏手术患者围手术期心血管评估和管理指南:执行摘要:美国心脏病学会/美国心脏协会实践指南工作组报告
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非心脏手术中的心肌损伤:复杂性与挑战

Myocardial injury in non-cardiac surgery: complexities and challenges.

作者信息

Kuthiah Navin, Er Chaozer

机构信息

Department of Internal Medicine, Woodlands Health Campus, Singapore.

出版信息

Singapore Med J. 2020 Jan;61(1):6-8. doi: 10.11622/smedj.2020004.

DOI:10.11622/smedj.2020004
PMID:32043159
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7900808/
Abstract

The term MINS (myocardial injury after non-cardiac surgery) was coined to broadly describe perioperative troponin elevation that is deemed to be due to a cardiac cause. However, this term is commonly used in literature to represent cases that do not fulfil the criteria for the diagnosis of myocardial infarction. Asymptomatic troponin elevation that does not fulfil the criteria for acute coronary syndrome in the perioperative setting has been shown to be associated with increased mortality. The discovery of MINS presents new opportunities to improve outcomes for surgical patients. Unfortunately, awareness of MINS among practitioners remains low and implementation of perioperative troponin monitoring is poor. Given its significance, the detection, management and prevention of MINS should not be overlooked.

摘要

术语“非心脏手术后心肌损伤(MINS)”被创造出来,用于广泛描述被认为由心脏原因导致的围手术期肌钙蛋白升高。然而,该术语在文献中通常用于表示不符合心肌梗死诊断标准的病例。围手术期出现的无症状肌钙蛋白升高,若不符合急性冠状动脉综合征的标准,已被证明与死亡率增加有关。MINS的发现为改善手术患者的预后带来了新机遇。不幸的是,从业者对MINS的认知度仍然很低,围手术期肌钙蛋白监测的实施情况也很差。鉴于其重要性,MINS的检测、管理和预防不容忽视。