Baccellieri Domenico, Ardita Vincenzo, Carta Niccolò, Melissano Germano, Chiesa Roberto
Department of Vascular Surgery, San Raffaele Hospital IRCCS, Vita-Salute San Raffaele University, Milan, Italy.
Department of Vascular Surgery, San Raffaele Hospital IRCCS, Vita-Salute San Raffaele University, Milan, Italy -
Int Angiol. 2020 Apr;39(2):105-111. doi: 10.23736/S0392-9590.20.04271-6. Epub 2020 Feb 5.
Varicose veins recurrence rate remained almost unchanged despite the constant technological advancement in its treatment. The aim of this study is to evaluate the variable accessory saphenous vein (ASV) anatomy at the sapheno-femoral junction (SFJ) as a possible risk factor for recurrent varicose vein (RVV) after great saphenous vein (GSV) radiofrequency thermal ablation (RTA).
Two-hundred consecutive patients affected by chronic venous disease (mean age 52.4±10.3 years; 187 women; CEAP C2-C6; 25.2±1.4), underwent to RTA from 2014 to 2016, at our Institute. Preoperatively all patients underwent duplex-ultrasound scanning, reporting the anatomical site, extension of reflux and the ASV anatomy at the SFJ. Duplex ultrasound and physical examination was performed postoperatively at 1, 6 and 12 months, and yearly thereafter.
Patients were divided in two groups based on the anatomical site of reflux: group A (N.=187) including GSV and SFJ, group B (N.=82) including SFJ reflux. There was no preoperative statistical difference between the two groups. At a mean follow-up of 29.7±2.4 months, a freedom from recurrent varicose vein and GSV recanalization was: 100% and 100% at 1 month, 95.9% and 99.1% at 1 year, 93.7% and 96.7% at 3 years, respectively. A higher rate of RVV was documented for patients in group A at 3-year of follow-up (P=0.042). Cox regression analysis found, among five potential predictors of outcome, that direct confluence of ASV in SFJ (HR=1.561; 95% CI: 1.0-7.04; P=0.032) was a negative predictors of 1-year RVV.
Sapheno-femoral junction morphology may affect recurrent varicose veins formation. In particular, a concomitant incompetence of the accessory saphenous vein or its directly confluence into the SFJ could represent an indication to simultaneous treatment by non-surgical techniques (RTA or laser) and avoid surgical ligation.
尽管静脉曲张治疗技术不断进步,但其复发率几乎保持不变。本研究旨在评估大隐静脉-股静脉交界处(SFJ)的可变副隐静脉(ASV)解剖结构,作为大隐静脉(GSV)射频热消融(RTA)后复发性静脉曲张(RVV)的可能危险因素。
2014年至2016年,在我们研究所,200例连续的慢性静脉疾病患者(平均年龄52.4±10.3岁;187名女性;CEAP C2-C6;25.2±1.4)接受了RTA。术前所有患者均接受双功超声扫描,报告反流的解剖部位、范围以及SFJ处的ASV解剖结构。术后1、6和12个月以及此后每年进行双功超声和体格检查。
根据反流的解剖部位将患者分为两组:A组(N.=187)包括GSV和SFJ,B组(N.=82)包括SFJ反流。两组术前无统计学差异。平均随访29.7±2.4个月时,1个月时无复发性静脉曲张和GSV再通的比例分别为100%和100%,1年时分别为95.9%和99.1%,3年时分别为93.7%和96.7%。随访3年时,A组患者的RVV发生率较高(P=0.042)。Cox回归分析发现,在五个潜在的预后预测因素中,ASV在SFJ处的直接汇合(HR=1.561;95%CI:1.0-7.04;P=0.032)是1年RVV的负性预测因素。
大隐静脉-股静脉交界处形态可能影响复发性静脉曲张的形成。特别是,副隐静脉的伴随功能不全或其直接汇入SFJ可能提示采用非手术技术(RTA或激光)同时治疗,并避免手术结扎。