Pós-Graduação em Medicina Interna, Universidade Federal do Paraná, Curitiba, PR, Brazil.
Division of Infectious Diseases, School of Medicine, Pontifícia Universidade Católica do Paraná, Curitiba, PR, Brazil; Laboratory of Emerging Infectious Diseases, School of Medicine, Pontifícia Universidade Católica do Paraná, Curitiba, PR, Brazil.
J Tissue Viability. 2020 May;29(2):135-137. doi: 10.1016/j.jtv.2020.02.001. Epub 2020 Feb 4.
Diabetic foot ulcer (DFU) is a complication of diabetes mellitus (DM) with established recurrence risk factors evaluating patients from United States or Europe. There are scarce studies in developing countries about these risks. The aim of this study was to evaluate risk factors associated with DFU recurrence in a Brazilian prospective cohort.
A prospective cohort of patients with healed DFU followed from January 2014 to June 2017 in Curitiba, Brazil. Periodic home visits from a specialist nurse in DFU were performed during the period of the study to evaluate recurrence of ulcer. The presence of risk factors in the group of patients that developed an ulcer in the follow-up period was compared with the presence of these factors in the group of patients without recurrence. At enrollment, 35 subjects presented a previous ulcer distal with complete healing to follow-up.
From 35 patients, 15 were male (43%) and the mean age was of 65.8 ± 10.9 years (48-85 year). Most patients were married with a low income (<US$ 250/month). The mean BMI was 26.5 ± 5.6 kg/cm. Seventy-four percent (26/35) had another comorbidity. The mean duration of DM until ulcer was 14.6 ± 5.2 years. The global mortality during the study (3 years) was 14%. The DFU recurred in 23 patients (65.7%). Both groups had similar findings, except by lower income (<US$ 250/month) in the group of recurrent DFU.
Recurrence of DFU is frequent and associated with low familiar income in a pilot Brazilian study.
糖尿病足溃疡（DFU）是糖尿病（DM）的一种并发症，其复发风险因素已在美国或欧洲得到了确立。关于这些风险，发展中国家的研究很少。本研究旨在评估巴西前瞻性队列中与 DFU 复发相关的风险因素。
本研究是对 2014 年 1 月至 2017 年 6 月期间在巴西库里蒂巴治愈的 DFU 患者进行的前瞻性队列研究。在研究期间，由一位专科护士对患者进行定期家访，以评估溃疡的复发情况。将在随访期间发生溃疡的患者组中的危险因素与未发生溃疡的患者组中的危险因素进行比较。在入组时，35 名患者有一个以前的溃疡，完全愈合至随访期。
在 35 名患者中，15 名男性（43%），平均年龄为 65.8±10.9 岁（48-85 岁）。大多数患者已婚，收入较低（<250 美元/月）。平均 BMI 为 26.5±5.6kg/cm。74%（26/35）有另一种合并症。糖尿病病程至溃疡的平均时间为 14.6±5.2 年。研究期间（3 年）总死亡率为 14%。23 名患者（65.7%）的 DFU 复发。两组患者的发现相似，除了复发 DFU 组的收入较低（<250 美元/月）。
在巴西的一项试点研究中，DFU 的复发很常见，且与家庭收入较低有关。
