婴儿在使用β-内酰胺类抗生素治疗后出现具有迁移性的局灶性癫痫发作 - 两例报告。
Focal seizures with a migrating aspect in infants treated with beta-lactam antibiotics - Report of two cases.
机构信息
Department of Infectious Disease and Neurology, Children's Hospital 1, Ho Chi Minh City, Viet Nam.
Department of Anesthesiology and Pediatric Surgical Critical Care, Necker-Enfants-Malades Hospital, AP-HP, Paris, France.
出版信息
Neurophysiol Clin. 2020 Apr;50(2):81-86. doi: 10.1016/j.neucli.2020.01.003. Epub 2020 Feb 7.
Seizures caused by beta-lactam antibiotics are relatively rare. However, they represent a clinically significant phenomenon and have been widely reported in all age groups. Here we describe two infants presenting subtle multifocal seizures with a migrating aspect on EEG during beta-lactam antibiotic treatment with agents from the carbapenem group (meropenem) and the cephalosporin group (ceftazidime).
β-内酰胺类抗生素引起的癫痫发作相对较少。然而，它们是一种具有临床意义的现象，在所有年龄段都有广泛报道。在此，我们描述了两名婴儿在使用碳青霉烯类（美罗培南）和头孢菌素类（头孢他啶）β-内酰胺类抗生素治疗期间出现脑电图上具有迁移特征的细微多灶性癫痫发作。
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