DeGrazia Taryn, Bromley Jennifer, Feldman Ron
Department of Dermatology, Emory University School of Medicine, Atlanta, GA.
Dermatol Online J. 2019 Nov 15;25(11):13030/qt4d91z9zx.
Mucous membrane pemphigoid (MMP) with ocular involvement, also referred to as ocular cicatricial pemphigoid, is a rare, autoimmune blistering disease that can have devastating effects for patients. The resulting corneal neovascularization, recurrent corneal abrasions, and ulceration can ultimately result in severe vision loss. We present a 64-year-old man with recalcitrant ocular MMP and consequently advanced corneal involvement that received bilateral keratoprostheses. This case highlights an aggressive but successful placement of bilateral keratoprostheses in recalcitrant ocular MMP, which restored his vision and ultimately his quality of life.
伴有眼部受累的黏膜类天疱疮(MMP),也称为瘢痕性类天疱疮,是一种罕见的自身免疫性水疱病,可对患者产生毁灭性影响。由此导致的角膜新生血管形成、复发性角膜擦伤和溃疡最终可导致严重视力丧失。我们报告一名64岁男性,患有顽固性眼部MMP并因此出现严重的角膜受累,接受了双侧角膜移植术。该病例突出了在顽固性眼部MMP中积极但成功地植入双侧角膜移植术,恢复了他的视力并最终改善了他的生活质量。