Institute of Traditional Medicine, National Yang-Ming University, Taipei, Taiwan.
Department of Chinese Medicine, Branch of Taipei, China Medical University Hospital, Taipei, Taiwan.
J Altern Complement Med. 2020 Apr;26(4):273-281. doi: 10.1089/acm.2019.0172. Epub 2020 Feb 11.
To evaluate the efficacy of acupuncture in helping antihypertensive drugs lower the hypertension of elderly patients in home health care. Randomized controlled trial. Subjects were recruited from Branch of Linsen, Chinese Medicine, and Kunming, Taipei City Hospital, Taipei, Taiwan. A total of 70 participants with hypertension in home health care were assigned randomly to the acupuncture group (35 participants) or the control group (35 participants). The acupuncture group received antihypertensive drugs plus acupuncture twice a week for 12 weeks, and the control group received antihypertensive drugs only. Acupuncture points SP10, SP6, LR3, ST36, and LI4 were used bilaterally. Each acupuncture treatment session lasted 30 min. All the subjects were instructed not to alter their diet, physical activity, or use of drugs. Blood pressure (BP), heart rate variability, and the Constitution in Chinese Medicine Questionnaire (CCMQ) were assessed at baseline and at 6 and 12 weeks from the baseline between 9 am and 10 am in all subjects. A total of 31 participants in each group completed the study. Within-group differences were observed in systolic BP (SBP) ( < 0.001), diastolic BP ( < 0.001), standard deviation of normal sinus beat intervals (SDNN) ( = 0.01), low frequency ( = 0.05), high frequency ( = 0.01), total power (TP) ( = 0.01), percentage of successive intervals that differ by more than 50 msec (PNN50) ( = 0.01), deficiency ( = 0.003), blood stasis ( = 0.02), and depression ( = 0.03) constitution. Significant between-group differences were observed in SBP ( = 0.001), SDNN ( = 0.008), and TP ( = 0.04). This study suggested that in the home health care hypertension population, antihypertensive drugs plus acupuncture may be more beneficial in lowering BP and in regulating autonomic nervous system activity than drugs alone. A longer follow-up and larger sample size should be considered in future studies to reveal the precise effect of acupuncture followed by evidence-based practice.
评价针灸在帮助居家老年高血压患者降低血压方面的疗效。随机对照试验。对象来自中国台北市林森中医昆明分所和台北市立联合医院。共有 70 名居家高血压患者被随机分为针灸组(35 名患者)和对照组(35 名患者)。针灸组在接受降压药物治疗的同时,每周接受两次针灸治疗,共 12 周;对照组仅接受降压药物治疗。两组均采用双侧 SP10、SP6、LR3、ST36 和 LI4 穴位。每次针灸治疗持续 30 分钟。所有患者均被要求不改变饮食、体力活动或药物使用。在上午 9 点至 10 点之间,所有患者在基线和基线后 6 周和 12 周时评估血压(BP)、心率变异性和中医体质问卷(CCMQ)。每组共有 31 名患者完成了研究。组内差异观察到收缩压(SBP)( < 0.001)、舒张压(DBP)( < 0.001)、窦性正常心搏间期标准差(SDNN)( = 0.01)、低频( = 0.05)、高频( = 0.01)、总功率(TP)( = 0.01)、连续间期差值超过 50ms 的百分比(PNN50)( = 0.01)、虚证( = 0.003)、血瘀证( = 0.02)和 抑郁证( = 0.03)。组间差异显著的有 SBP( = 0.001)、SDNN( = 0.008)和 TP( = 0.04)。本研究表明,在居家高血压人群中,降压药物联合针灸可能比单纯药物治疗更有利于降低血压和调节自主神经系统活动。未来的研究应该考虑更长的随访和更大的样本量,以揭示针灸后的精确效果,并为循证实践提供依据。