用于超痕量测定双氯芬酸的首个电化学传感器（羧基功能化多壁碳纳米管修饰的丝网印刷碳电极）

First Electrochemical Sensor (Screen-Printed Carbon Electrode Modified with Carboxyl Functionalized Multiwalled Carbon Nanotubes) for Ultratrace Determination of Diclofenac.

作者信息

Sasal Agnieszka, Tyszczuk-Rotko Katarzyna, Wójciak Magdalena, Sowa Ireneusz

机构信息

Faculty of Chemistry, Institute of Chemical Sciences, Maria Curie-Skłodowska University, 20-031 Lublin, Poland.

Department of Analytical Chemistry, Medical University of Lublin, 20-093 Lublin, Poland.

出版信息

Materials (Basel). 2020 Feb 8;13(3):781. doi: 10.3390/ma13030781.

A simple, sensitive and time-saving differential-pulse adsorptive stripping voltammetric (DPAdSV) procedure using a screen-printed carbon electrode modified with carboxyl functionalized multiwalled carbon nanotubes (SPCE/MWCNTs-COOH) for the determination of diclofenac (DF) is presented. The sensor was characterized using optical profilometry, SEM, and cyclic voltammetry (CV). The use of carboxyl functionalized MWCNTs as a SPCE modifier improved the electron transfer process and the active surface area of sensor. Under optimum conditions, very sensitive results were obtained with a linear range of 0.1-10.0 nmol L and a limit of detection value of 0.028 nmol L. The SPCE/MWCNTs-COOH also exhibited satisfactory repeatability, reproducibility, and selectivity towards potential interferences. Moreover, for the first time, the electrochemical sensor allows determining the real concentrations of DF in environmental water samples without sample pretreatment steps.

本文介绍了一种简单、灵敏且省时的差分脉冲吸附溶出伏安法（DPAdSV），该方法使用羧基功能化多壁碳纳米管修饰的丝网印刷碳电极（SPCE/MWCNTs-COOH）来测定双氯芬酸（DF）。使用光学轮廓仪、扫描电子显微镜（SEM）和循环伏安法（CV）对该传感器进行了表征。将羧基功能化的多壁碳纳米管用作SPCE修饰剂，改善了电子转移过程和传感器的活性表面积。在最佳条件下，获得了非常灵敏的结果，线性范围为0.1 - 10.0 nmol/L，检测限为0.028 nmol/L。SPCE/MWCNTs-COOH对潜在干扰物也表现出令人满意的重复性、再现性和选择性。此外，该电化学传感器首次无需样品预处理步骤即可测定环境水样中DF的实际浓度。