Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota.
J Arthroplasty. 2020 Mar;35(3S):S40-S44. doi: 10.1016/j.arth.2019.10.055.
Two-stage exchange arthroplasty remains the gold standard for chronic total knee arthroplasty (TKA) and total hip arthroplasty infections in North America. Cement spacers impregnated with high-dose antibiotics have been successfully used in the interim period of the 2-stage exchange process. A number of spacers have been described; however, this article will focus on articulating spacers. In the presence of an intact extensor mechanism (for TKA), reasonable soft tissue envelope, and adequate bone, articulating antibiotic spacers provide several advantages. These include an infection eradication rate of approximately 90%, higher range of motion after reimplantation, and lower complication rates when compared with nonarticulating spacers. In the appropriate patient, articulating antibiotic spacers are an effective and a safe treatment for infected TKAs and total hip arthroplasties.
双阶段关节置换术仍然是北美慢性全膝关节置换术(TKA)和全髋关节置换术感染的金标准。在双阶段关节置换过程的间歇期,已成功使用高剂量抗生素浸渍的水泥间隔物。已经描述了许多间隔物;然而,本文将重点介绍关节式间隔物。在存在完整的伸肌机制(用于 TKA)、合理的软组织包囊和足够的骨骼的情况下,关节式抗生素间隔物具有几个优点。这些优点包括约 90%的感染清除率、再植入后的更大运动范围以及与非关节式间隔物相比更低的并发症发生率。在适当的患者中,关节式抗生素间隔物是治疗感染性 TKA 和全髋关节置换术的有效且安全的方法。