Department of Orthopedic Surgery, Joint Replacement, Indiana University Health Physicians, Fishers, IN.
Department of Orthopedic Surgery, Joint Replacement, Rothman Orthopaedic Institute, New York, NY.
J Arthroplasty. 2020 Mar;35(3S):S57-S62. doi: 10.1016/j.arth.2019.10.049.
Periprosthetic joint infection represents a serious complication following total knee arthroplasty. In the setting of chronic or age-indeterminate total knee arthroplasty infection, a 2-staged approach has been traditionally the preferred method of treatment over single-stage debridement and reimplantation debridement or debridement, antibiotics and implant retention. Two-stage is the preferred treatment method in North America and has demonstrated better overall success than the single stage techniques. Additionally, the 2-stage method is the preferred treatment for difficult to treat pathogens as well as in patients who have already undergone a previous revision procedure. An articulating prefabricated antibiotic spacer has entered the armamentarium of 2-stage revision knee surgery, and has demonstrated comparable results to custom and static spacers in terms of the primary goal of infection control. Importantly, the potential for enhanced mobility and function hold promise by safely providing a more "livable" knee during the convalescent period prior to definitive reimplantation.
人工关节周围感染是全膝关节置换术后的一种严重并发症。在慢性或年龄不明的全膝关节置换术后感染的情况下,两期手术一直是治疗的首选方法,而不是一期清创和再植入清创或清创、抗生素和植入物保留。两期手术是北美的首选治疗方法,其总体成功率优于单期手术技术。此外,两期手术方法是治疗难治性病原体的首选方法,也是已经接受过先前翻修手术的患者的首选治疗方法。一种可活动的预制抗生素间隔物已应用于两期翻修膝关节手术中,在控制感染这一首要目标方面,其结果与定制和静态间隔物相当。重要的是,通过在确定性再植入前的康复期安全地提供更“可活动”的膝关节,增强活动能力和功能的潜力带来了希望。