Department of Obstetrics and Gynecology, Seoul National University Hospital, Seoul, South Korea.
Department of Obstetrics and Gynecology, Seoul National University College of Medicine, 103 Daehak-ro, Jongno-gu, Seoul, 03080, South Korea.
Int Urogynecol J. 2020 Oct;31(10):2043-2049. doi: 10.1007/s00192-020-04229-0. Epub 2020 Feb 11.
The aim of this study was to compare treatment outcomes 1 year after uterosacral ligament suspension (USLS) with or without concomitant anterior repair (AR) for anterior vaginal wall prolapse resolved under simulated apical support.
This retrospective cohort study included 179 women who underwent USLS with or without concomitant AR for Pelvic Organ Prolapse Quantification (POPQ) stage 2-4 anterior vaginal wall prolapse resolved under simulated apical support, and who completed a 1-year follow-up. The primary outcome was composite surgical failure defined as anterior anatomical recurrence (point Ba>0), symptomatic recurrence (presence of vaginal bulge symptoms), or retreatment for prolapse. Secondary outcomes included changes in POPQ values and Urogenital Distress Inventory-6 (UDI-6) scores, perioperative outcomes, and complications.
Eighty-six women underwent concomitant AR, and 93 did not. The group receiving AR had more advanced anterior and apical prolapse. Surgical failure rates were significantly higher in the group not receiving AR than in the group receiving AR (21.5% vs 7.0%, p < 0.01). However, there were no differences in the mean point Ba and C values and UDI-6 scores through 12 months postoperatively between the two groups. Operating times were longer, and adverse events, such as immediate postoperative urinary retention and minor wound complications, were more frequent in the group receiving AR (p < 0.05).
Concomitant AR at the time of USLS seems to reduce the recurrence of anterior vaginal wall prolapse without significant morbidity. Considering the small difference in anatomical outcomes, a longer follow-up period will be required to confirm this.
本研究旨在比较经阴道骶骨固定术(USLS)联合或不联合前修补术(AR)治疗模拟顶托下缓解的前阴道壁脱垂 1 年的治疗效果。
本回顾性队列研究纳入了 179 例因 Pelvic Organ Prolapse Quantification(POPQ)2-4 期前阴道壁脱垂,模拟顶托下缓解而接受 USLS 联合或不联合 AR 的患者,且均完成了 1 年随访。主要结局为复合手术失败,定义为前解剖学复发(Ba 点>0)、症状复发(存在阴道膨出症状)或因脱垂再次治疗。次要结局包括 POPQ 值和 Urogenital Distress Inventory-6(UDI-6)评分的变化、围手术期结局和并发症。
86 例患者接受了 AR,93 例未接受。接受 AR 的患者前壁和顶壁脱垂更严重。未接受 AR 的患者手术失败率显著高于接受 AR 的患者(21.5% vs. 7.0%,p<0.01)。然而,两组患者术后 12 个月的 Ba 和 C 点均值以及 UDI-6 评分均无差异。接受 AR 的患者手术时间较长,且术后即刻发生尿潴留和轻微伤口并发症等不良事件更为频繁(p<0.05)。
USLS 时联合 AR 似乎可以降低前阴道壁脱垂的复发率,而不会显著增加发病率。考虑到解剖学结局的微小差异,需要更长的随访时间来证实这一点。