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自体颌下腺导管重建腮腺导管缺损在颊癌中的初步应用及评价。

Preliminary application and evaluation of autograft reconstruction of parotid duct defect with submandibular gland duct for buccal cancer.

机构信息

Research Center of Carcinogenesis and Targeted Therapy, Xiangya Hospital, Central South University, Changsha, China.

Department of Stomatology, The Third Xiangya Hospital, Central South University, Changsha, China.

出版信息

Acta Otolaryngol. 2020 May;140(5):427-432. doi: 10.1080/00016489.2020.1718750. Epub 2020 Feb 12.

Abstract

We aimed to preserve parotid function in patients with buccal carcinoma by applying a new surgical protocol based on reconstruction of parotid ductal defect with submandibular gland ductal. The aim of this study is to introduce the method of autologous submandibular gland duct reconstruction for the treatment of parotid duct defect in buccal carcinoma, and to evaluate its clinical application in follow-up. A total of 28 patients with buccal carcinoma who underwent buccal and neck combined with radical surgery and vascularized flap transplantation were enrolled. Function of the reconstructed duct was reviewed in 6 months after surgery. Both groups achieved good short-term results within 1 month after surgery. The 6-month postoperative angiography examination of the submandibular gland duct showed that 6% of patients in the submandibular gland duct graft group had a blockage or was not smooth. At the same time, 45% of the patients in the vein graft group had failure or obstruction, and the VAS score of pain was higher than that of the submandibular gland ductal graft group ( < .05). Compared with vein grafting, the reconstruction of parotid ductal defect with submandibular gland ductal graft has better long-term effects.

摘要

我们旨在通过应用一种新的基于颌下腺导管修复腮腺导管缺损的手术方案来保留颊癌患者的腮腺功能。本研究旨在介绍自体颌下腺导管重建治疗颊癌腮腺导管缺损的方法,并评估其在随访中的临床应用。共纳入 28 例颊癌患者,均行颊颈部联合根治术及血管化皮瓣移植。术后 6 个月复查重建导管功能。两组患者术后 1 个月内均获得良好的短期效果。术后 6 个月颌下腺导管血管造影检查显示,颌下腺导管移植组有 6%的患者出现阻塞或不畅通,静脉移植组有 45%的患者出现失败或阻塞,且疼痛 VAS 评分高于颌下腺导管移植组(<0.05)。与静脉移植相比,颌下腺导管重建治疗腮腺导管缺损具有更好的长期效果。

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