From the Department of Gastroenterology, The Second Affiliated Hospital, Jiaxing University, Jiaxing, Zhejiang Province.
Department of Nuclear Medicine, Changhai Hospital.
Clin Nucl Med. 2020 May;45(5):e245-e248. doi: 10.1097/RLU.0000000000002962.
We present 2 cases of pancreatic neuroendocrine tumor with diffuse involvement of the entire pancreas. One case with G2 pancreatic neuroendocrine tumor showed nearly normal pancreatic shape and signal intensity on MRI, normal pancreatic FDG uptake, and diffuse pancreatic Ga-DOTATOC uptake. The other case with G3 pancreatic neuroendocrine tumor showed diffusely enlarged pancreas with abnormal MR signal intensity and increased FDG uptake. These 2 cases indicate that neuroendocrine tumor should be included in the differential diagnosis of diffuse pancreatic diseases. Somatostatin receptor imaging may be helpful for the diagnosis of diffuse pancreatic neuroendocrine tumor in equivocal cases.
我们报告 2 例胰腺神经内分泌肿瘤，其弥漫累及整个胰腺。1 例 G2 级胰腺神经内分泌肿瘤在 MRI 上显示胰腺形态和信号强度基本正常，胰腺摄取 FDG 正常，胰腺弥漫摄取 Ga-DOTATOC。另 1 例 G3 级胰腺神经内分泌肿瘤显示胰腺弥漫性肿大，MR 信号强度异常，FDG 摄取增加。这 2 例表明神经内分泌肿瘤应包括在弥漫性胰腺疾病的鉴别诊断中。生长抑素受体显像可能有助于诊断不典型弥漫性胰腺神经内分泌肿瘤。
