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骨髓移植受者感染堪萨斯分枝杆菌致脓毒性关节炎

Septic Arthritis Caused by Mycobacterium Kansasii in a Bone Marrow Transplant Recipient.

机构信息

Departments of Pediatrics.

Orthopaedic Surgery, Hokkaido University Graduate School of Medicine, Sapporo, Japan.

出版信息

J Pediatr Hematol Oncol. 2020 Nov;42(8):e791-e794. doi: 10.1097/MPH.0000000000001746.

DOI:10.1097/MPH.0000000000001746
PMID:32049768
Abstract

We report an 18-year-old female individual with septic arthritis due to Mycobacterium kansasii. Three years and 6 months before arthritis, the patient underwent bone marrow transplantation and developed severe chronic graft-versus-host disease. The arthritis was refractory to medication, and she underwent joint lavage of the right foot, hip joint, and elbow joint. After surgery, her joint symptoms were relieved, and chronic graft-versus-host disease remitted more easily. It is important that we maintain a high index of suspicion for mycobacterial arthritis and diagnose it early when immunosuppressed patients experience chronic pain and joint swelling.

摘要

我们报告了一例由堪萨斯分枝杆菌引起的败血症性关节炎的 18 岁女性个体。在关节炎发生前 3 年零 6 个月,该患者接受了骨髓移植,并发生严重的慢性移植物抗宿主病。关节炎对药物治疗有抗药性,她接受了右脚、髋关节和肘关节的关节冲洗术。手术后,她的关节症状得到缓解,慢性移植物抗宿主病更容易缓解。重要的是,当免疫抑制患者出现慢性疼痛和关节肿胀时,我们要保持对分枝杆菌性关节炎的高度怀疑,并尽早诊断。

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