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光学相干断层扫描和血流储备分数指导下治疗表现为急性心肌梗死的编织状冠状动脉异常:一例报告

Optical coherence tomography and fractional flow reserve guided treatment of woven coronary artery anomaly presenting as acute myocardial infarction: A case report.

作者信息

Wang Fangfang, Han Jiangli, Guo Lijun

机构信息

Department of Cardiology and Institute of Vascular Medicine, Peking University Third Hospital.

NHC Key Laboratory of Cardiovascular Molecular Biology and Regulatory Peptides.

出版信息

Medicine (Baltimore). 2020 Feb;99(7):e19163. doi: 10.1097/MD.0000000000019163.

DOI:10.1097/MD.0000000000019163
PMID:32049845
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7035091/
Abstract

RATIONALE

Woven coronary artery is a very rare congenital anomaly which may lead to acute coronary syndrome in previous literatures. At present, there is no consensus on the treatment of this coronary artery abnormality.

PATIENT CONCERNS

A 48-year-old male was admitted to the other hospital because of persistent chest pain. The electrocardiogram showed an ST-segment elevation in the v1-v5 lead and the patient was diagnosed with acute anterior myocardial infarction. Coronary angiography revealed 2 lumens in the proximal segment of the left anterior descending artery. Then the patient was transferred to our hospital for further diagnosis and treatment.

DIAGNOSES

The patient was diagnosed with acute myocardial infarction and woven coronary. Transthoracic echocardiography showed left ventricular anterior wall segmental motor abnormalities.

INTERVENTIONS

Optical coherence tomography (OCT) and fractional flow reserve (FFR) guided percutaneous coronary intervention was performed successfully.

OUTCOMES

During the follow-up period of 4 years, the patient remained asymptomatic and no adverse events.

LESSONS

Although the significance of blood flow limitation in one of the lumens detected by FFR is unclear, this strategy of OCT and FFR-guided treatment in woven coronary artery combined with acute coronary events still shows its feasibility.

摘要

理论依据

编织状冠状动脉是一种非常罕见的先天性异常,在以往文献中可能导致急性冠状动脉综合征。目前,对于这种冠状动脉异常的治疗尚无共识。

患者情况

一名48岁男性因持续性胸痛入住其他医院。心电图显示V1-V5导联ST段抬高,患者被诊断为急性前壁心肌梗死。冠状动脉造影显示左前降支近端有2个管腔。随后患者转至我院进一步诊治。

诊断

患者被诊断为急性心肌梗死和编织状冠状动脉。经胸超声心动图显示左心室前壁节段性运动异常。

干预措施

成功进行了光学相干断层扫描(OCT)和血流储备分数(FFR)引导下的经皮冠状动脉介入治疗。

结果

在4年的随访期内,患者无症状,未发生不良事件。

经验教训

尽管FFR检测到的其中一个管腔血流受限的意义尚不清楚,但这种OCT和FFR引导下治疗编织状冠状动脉合并急性冠状动脉事件的策略仍显示出其可行性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f466/7035091/85d164570d6c/medi-99-e19163-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f466/7035091/7646546024e5/medi-99-e19163-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f466/7035091/85d164570d6c/medi-99-e19163-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f466/7035091/7646546024e5/medi-99-e19163-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f466/7035091/85d164570d6c/medi-99-e19163-g002.jpg

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本文引用的文献

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Histopathologic Insights Into the Honeycomb-Like Structure in the Coronary Artery: In Vivo Multimodality Imaging Assessment With Directional Coronary Atherectomy.冠状动脉蜂窝状结构的组织病理学见解:冠状动脉定向旋切术的体内多模态成像评估
JACC Cardiovasc Interv. 2018 Oct 8;11(19):e157-e159. doi: 10.1016/j.jcin.2018.07.014.
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Woven coronary anomaly leading to silent myocardial infarction: A case report.导致无症状心肌梗死的编织状冠状动脉异常:一例报告。
Medicine (Baltimore). 2017 Nov;96(44):e8302. doi: 10.1097/MD.0000000000008302.
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Woven coronary artery anomaly presenting as sudden cardiac death.
编织状冠状动脉异常:一项偶然发现及文献综述
Case Rep Cardiol. 2022 Apr 14;2022:3235663. doi: 10.1155/2022/3235663. eCollection 2022.
表现为心源性猝死的编织状冠状动脉异常。
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Woven Coronary Artery Disease Successfully Managed with Percutaneous Coronary Intervention: A New Case Report.经皮冠状动脉介入术成功治疗编织型冠状动脉疾病:一例新病例报告
Case Rep Cardiol. 2015;2015:516539. doi: 10.1155/2015/516539. Epub 2015 Sep 30.
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Chronic Ischemia Induced by Woven Coronary Artery Anomaly with Typical Atrial Flutter: Insights from Multiple Imaging Devices.
Intern Med. 2015;54(17):2185-9. doi: 10.2169/internalmedicine.54.4333. Epub 2015 Sep 1.
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Fractional flow reserve versus angiography for guiding percutaneous coronary intervention: a meta-analysis.血流储备分数与血管造影术在指导经皮冠状动脉介入治疗中的比较:一项荟萃分析。
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J Am Coll Cardiol. 2010 Jul 13;56(3):177-84. doi: 10.1016/j.jacc.2010.04.012. Epub 2010 May 28.