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Med Care. 2013 Sep;51(9):797-805. doi: 10.1097/MLR.0b013e31829a4fb4.
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Implementation of G-computation on a simulated data set: demonstration of a causal inference technique.在模拟数据集上实施 G 计算:因果推理技术的演示。
Am J Epidemiol. 2011 Apr 1;173(7):731-8. doi: 10.1093/aje/kwq472. Epub 2011 Mar 16.
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评估医院绩效改善的净效益:使用分层回归模型的G计算法

Estimating the Net Benefit of Improvements in Hospital Performance: G-Computation With Hierarchical Regression Models.

作者信息

Austin Peter C, Lee Douglas S

机构信息

ICES.

Institute of Health Management, Policy, and Evaluation, University of Toronto.

出版信息

Med Care. 2020 Jul;58(7):651-657. doi: 10.1097/MLR.0000000000001312.

DOI:10.1097/MLR.0000000000001312
PMID:32049879
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7289139/
Abstract

BACKGROUND

It is important to be able to estimate the anticipated net population benefit if the performance of hospitals is improved to specific standards.

OBJECTIVE

The objective of this study was to show how G-computation can be used with random effects logistic regression models to estimate the absolute reduction in the number of adverse events if the performance of some hospitals within a region was improved to meet specific standards.

RESEARCH DESIGN

A retrospective cohort study using health care administrative data.

SUBJECTS

Patients hospitalized with acute myocardial infarction in the province of Ontario in 2015.

RESULTS

Of 18,067 patients hospitalized at 97 hospitals, 1441 (8.0%) died within 30 days of hospital admission. If the performance of the 25% of hospitals with the worst performance had their performance changed to equal that of the 75th percentile of hospital performance, 3.5 deaths within 30 days would be avoided [95% confidence interval (CI): 0.4-26.5]. If the performance of those hospitals whose performance was worse than that of an average hospital had their performance changed to that of an average hospital, 6.0 deaths would be avoided (95% CI: 0.7-47.0). If the performance of the 75% of hospitals with the worst performance had their performance changed to equal that of the 25th percentile of hospital performance, 11.0 deaths would be avoided (95% CI: 1.2-79.0).

CONCLUSION

G-computation can be used to estimate the net population reduction in the number of adverse events if the performance of hospitals was improved to specific standards.

摘要

背景

如果医院的绩效提升到特定标准,能够估计预期的净人群效益是很重要的。

目的

本研究的目的是展示如何将G计算与随机效应逻辑回归模型结合使用,以估计如果一个地区内某些医院的绩效提升到符合特定标准,不良事件数量的绝对减少量。

研究设计

一项使用医疗保健管理数据的回顾性队列研究。

研究对象

2015年安大略省因急性心肌梗死住院的患者。

结果

在97家医院住院的18067名患者中,1441名(8.0%)在入院后30天内死亡。如果绩效最差的25%的医院将其绩效提升至与第75百分位的医院绩效相当,则可避免3.5例30天内的死亡[95%置信区间(CI):0.4 - 26.5]。如果绩效比平均水平差的那些医院将其绩效提升至平均水平,则可避免6.0例死亡(95%CI:0.7 - 47.0)。如果绩效最差的75%的医院将其绩效提升至与第25百分位的医院绩效相当,则可避免11.0例死亡(95%CI:1.2 - 79.0)。

结论

如果医院的绩效提升到特定标准,G计算可用于估计不良事件数量的净人群减少量。