Scheie Eye Institute, Department of Ophthalmology.
Department of Dermatology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, U.S.A.
Ophthalmic Plast Reconstr Surg. 2020 Jul/Aug;36(4):e90-e91. doi: 10.1097/IOP.0000000000001603.
A 70-year-old woman with a history of Demodex blepharitis presented with a 1-year history of red-yellow nodules in the tarsus of her eyelids. Excisional biopsy revealed robust caseating granulomatous inflammation, consistent with the diagnosis of lupus miliaris disseminatus faciei. Lupus miliaris disseminatus faciei is a rare granulomatous dermatosis of unknown etiology. Estimated 200 cases have been reported to date, but none have been reported affecting the posterior lamellae of the eyelids. Lupus miliaris disseminatus faciei classically presents as symmetric yellow or brown papules on the central face and eyelid skin. Infectious etiologies and systemic granulomatous disease need to be ruled out with histologic staining and serologies.
一位 70 岁的女性,有螨虫性睑缘炎病史,现因眼睑皮肤出现红色-黄色结节 1 年就诊。切除活检显示为丰富的干酪样肉芽肿性炎症,符合播散性面部粟粒状狼疮的诊断。播散性面部粟粒状狼疮是一种病因不明的罕见肉芽肿性皮肤病。迄今为止,估计已有 200 例病例报告,但尚无报道称其影响眼睑后板。播散性面部粟粒状狼疮经典表现为对称的黄色或棕色丘疹,位于面部和眼睑皮肤的中央。需要通过组织学染色和血清学检查排除感染性病因和系统性肉芽肿性疾病。