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[肢体或骨盆/腹膜后肉瘤新辅助/辅助放疗及手术后的晚期并发症：预防措施]

[Late complications following neo-/adjuvant radiotherapy and surgery for sarcomas of the extremities or pelvis/retroperitoneum : Preventative measures].

作者信息

Jentsch C, Hofbauer C, Makocki S, Troost E

机构信息

Klinik und Poliklinik für Strahlentherapie und Radioonkologie, Universitätsklinikum Carl Gustav Carus, Technische Universität Dresden, Fetscherstraße 74, 01307, Dresden, Deutschland.

OncoRay - National Center for Radiation Research in Oncology, Dresden, Deutschland.

出版信息

Orthopade. 2020 Feb;49(2):177-182. doi: 10.1007/s00132-020-03881-0.

DOI:10.1007/s00132-020-03881-0
PMID:32052075
Abstract

Radiotherapy is one of the pillars in the multimodal therapy of sarcomas of the extremities or pelvis/retroperitoneum. It can be delivered prior to or following surgery. Novel radiation techniques, such as intensity-modulated radiotherapy using high-energy photons or protons, contribute to the reduction of acute and late toxicities. This review article summarizes these concepts.

摘要

放射治疗是四肢或骨盆/腹膜后肉瘤多模式治疗的支柱之一。它可以在手术前或手术后进行。新型放射技术，如使用高能光子或质子的调强放射治疗，有助于减少急性和晚期毒性。这篇综述文章总结了这些概念。

相似文献

1
[Late complications following neo-/adjuvant radiotherapy and surgery for sarcomas of the extremities or pelvis/retroperitoneum : Preventative measures].[肢体或骨盆/腹膜后肉瘤新辅助/辅助放疗及手术后的晚期并发症：预防措施]
Orthopade. 2020 Feb;49(2):177-182. doi: 10.1007/s00132-020-03881-0.
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Cancer Radiother. 2022 Feb-Apr;26(1-2):377-387. doi: 10.1016/j.canrad.2021.11.023. Epub 2021 Dec 24.
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[Brachytherapy for sarcomas].[肉瘤的近距离放射治疗]
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Radiation Therapy for Soft Tissue Sarcoma: Indications and Controversies for Neoadjuvant Therapy, Adjuvant Therapy, Intraoperative Radiation Therapy, and Brachytherapy.软组织肉瘤的放射治疗：新辅助治疗、辅助治疗、术中放射治疗和近距离放射治疗的适应证及争议
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本文引用的文献

1
Survival Benefit of the Surgical Management of Retroperitoneal Sarcoma in a Reference Center: A Nationwide Study of the French Sarcoma Group from the NetSarc Database.腹膜后肉瘤外科治疗的生存获益：来自 NetSarc 数据库的法国肉瘤研究组的全国性研究。
Ann Surg Oncol. 2019 Jul;26(7):2286-2293. doi: 10.1245/s10434-019-07421-9. Epub 2019 May 7.
2
Preoperative or postoperative radiotherapy versus surgery alone for retroperitoneal sarcoma: a case-control, propensity score-matched analysis of a nationwide clinical oncology database.术前或术后放疗与单纯手术治疗腹膜后肉瘤的比较：全国临床肿瘤数据库的病例对照、倾向评分匹配分析。
Lancet Oncol. 2016 Jul;17(7):966-975. doi: 10.1016/S1470-2045(16)30050-X. Epub 2016 May 17.
3
Significant Reduction of Late Toxicities in Patients With Extremity Sarcoma Treated With Image-Guided Radiation Therapy to a Reduced Target Volume: Results of Radiation Therapy Oncology Group RTOG-0630 Trial.
肢体肉瘤患者采用影像引导放射治疗缩小靶区后晚期毒性显著降低：放射肿瘤学组RTOG-0630试验结果
J Clin Oncol. 2015 Jul 10;33(20):2231-8. doi: 10.1200/JCO.2014.58.5828. Epub 2015 Feb 9.
4
Selection of patients for radiotherapy with protons aiming at reduction of side effects: the model-based approach.质子放射治疗中基于模型的方法以减少副作用为目标的患者选择。
Radiother Oncol. 2013 Jun;107(3):267-73. doi: 10.1016/j.radonc.2013.05.007. Epub 2013 Jun 5.
5
Phase 2 study of preoperative image-guided intensity-modulated radiation therapy to reduce wound and combined modality morbidities in lower extremity soft tissue sarcoma.术前图像引导调强放疗降低下肢软组织肉瘤创面及联合治疗并发症的Ⅱ期研究。
Cancer. 2013 May 15;119(10):1878-84. doi: 10.1002/cncr.27951. Epub 2013 Feb 19.
6
Long-term results following postoperative radiotherapy for soft tissue sarcomas of the extremity.肢体软组织肉瘤术后放疗的长期结果。
Int J Radiat Oncol Biol Phys. 2012 Nov 15;84(4):1003-9. doi: 10.1016/j.ijrobp.2012.01.074. Epub 2012 May 5.
7
Intensity modulated radiation therapy for retroperitoneal sarcoma: a case for dose escalation and organ at risk toxicity reduction.调强放射治疗用于腹膜后肉瘤：剂量递增与降低危及器官毒性的实例
Sarcoma. 2003;7(3-4):137-48. doi: 10.1080/13577140310001644751.
8
Intensity modulated radiation-therapy for preoperative posterior abdominal wall irradiation of retroperitoneal liposarcomas.调强放射治疗用于术前对腹膜后脂肪肉瘤进行后腹壁照射。
Int J Radiat Oncol Biol Phys. 2007 Jan 1;67(1):164-70. doi: 10.1016/j.ijrobp.2006.08.023. Epub 2006 Nov 2.
9
Intraoperative electron boost radiation followed by moderate doses of external beam radiotherapy in limb-sparing treatment of patients with extremity soft-tissue sarcoma.肢体软组织肉瘤患者保肢治疗中，术中电子束增强放疗后联合中等剂量外照射放疗。
Int J Radiat Oncol Biol Phys. 2006 Apr 1;64(5):1416-23. doi: 10.1016/j.ijrobp.2005.10.009. Epub 2006 Jan 18.
10
Late radiation morbidity following randomization to preoperative versus postoperative radiotherapy in extremity soft tissue sarcoma.肢体软组织肉瘤术前与术后放疗随机分组后的晚期放射并发症
Radiother Oncol. 2005 Apr;75(1):48-53. doi: 10.1016/j.radonc.2004.12.020.