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Successful treatment of Hodgkin lymphoma-like EBV-associated post-transplant lymphoproliferative disorder following allogeneic hematopoietic stem cell transplantation with nivolumab.

作者信息

Wada Fumiya, Kondo Tadakazu, Nakamura Momoko, Chonabayashi Kazuhisa, Nishikori Momoko, Hishizawa Masakatsu, Yamashita Kouhei, Takaori-Kondo Akifumi

机构信息

Department of Hematology and Oncology, Graduate School of Medicine, Kyoto University, 54 Shogoin Kawaharacho Sakyo-ku, Kyoto, 606-8507, Japan.

出版信息

Ann Hematol. 2020 Apr;99(4):887-889. doi: 10.1007/s00277-020-03960-4. Epub 2020 Feb 12.

DOI:10.1007/s00277-020-03960-4
PMID:32052134
Abstract
摘要

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1
Successful treatment of Hodgkin lymphoma-like EBV-associated post-transplant lymphoproliferative disorder following allogeneic hematopoietic stem cell transplantation with nivolumab.异基因造血干细胞移植后使用纳武单抗成功治疗霍奇金淋巴瘤样EB病毒相关移植后淋巴细胞增殖性疾病
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2
Classical Hodgkin lymphoma-like post-transplant lymphoproliferative disease after allogeneic stem cell transplantation for primary myelofibrosis is successfully treated with nivolumab: A case report.异基因造血干细胞移植后发生类似于经典型霍奇金淋巴瘤的移植后淋巴组织增生性疾病，成功接受纳武利尤单抗治疗：一例报告。
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Epstein-Barr virus reactivation in allogeneic stem cell transplantation is highly related to cytomegalovirus reactivation.同种异体干细胞移植中 EB 病毒的再激活与巨细胞病毒的再激活高度相关。
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Post-transplant lymphoproliferative disease and other Epstein-Barr virus diseases in allogeneic haematopoietic stem cell transplantation after introduction of monitoring of viral load by polymerase chain reaction.引入聚合酶链反应监测病毒载量后异基因造血干细胞移植中的移植后淋巴细胞增殖性疾病及其他EB病毒疾病
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Heterogeneity in clinical course of EBV-associated lymphoproliferative disorder after allogeneic stem cell transplantation.异基因造血干细胞移植后EB病毒相关淋巴增殖性疾病临床病程的异质性。
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Low-dose pembrolizumab induced complete radiologic and molecular response of posttransplant lymphoproliferative disorder presenting as classical Hodgkin lymphoma.低剂量派姆单抗诱导移植后淋巴组织增生性疾病（表现为经典型霍奇金淋巴瘤）出现完全的影像学和分子反应。
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引用本文的文献

1
Post-hematopoietic stem cell transplantation relapse: Role of checkpoint inhibitors.造血干细胞移植后复发：检查点抑制剂的作用
Health Sci Rep. 2022 Mar 8;5(2):e536. doi: 10.1002/hsr2.536. eCollection 2022 Mar.
2
High numbers of programmed cell death-1-positive tumor infiltrating lymphocytes correlate with early onset of post-transplant lymphoproliferative disorder.高数量的程序性细胞死亡受体 1 阳性肿瘤浸润淋巴细胞与移植后淋巴组织增生性疾病的早期发病相关。
Int J Hematol. 2021 Jul;114(1):53-64. doi: 10.1007/s12185-021-03129-3. Epub 2021 Mar 25.
3
Current Clinical Applications and Future Perspectives of Immune Checkpoint Inhibitors in Non-Hodgkin Lymphoma.
免疫检查点抑制剂在非霍奇金淋巴瘤中的当前临床应用和未来展望。
J Immunol Res. 2020 Oct 29;2020:9350272. doi: 10.1155/2020/9350272. eCollection 2020.