Neurology Department, Multimedica Hospital, Castellanza, Italy.
Istituto Nazionale Riposo e Cura per Anziani (INRCA), Fermo, Italy.
Am J Alzheimers Dis Other Demen. 2020 Jan-Dec;35:1533317519899544. doi: 10.1177/1533317519899544.
Sixty-nine dyads of patients with Alzheimer's disease and primary caregivers have been followed up for 1 year to evaluate cognitive (Mini-Mental State Examination), functional (Instrumental Activities of Daily Living), and behavioral (Neuropsychiatric Inventory) decline of patient in relation to burden (Caregiver Burden Inventory), stress (Relative Stress Scale), anxiety (State-Trait Anxiety Inventory Y), and depression (Beck Depression Inventory) reported by the caregivers. After 1 year of observation, cognitive and functional scores worsened while behavioral problems remained unchanged and relatively mild in patients. After 1 year, caregivers' scores of scales of anxiety and depression decreased significantly, while stress scores remained unchanged and burden slightly increased. In our opinion, the unexpected improvement in psychological situation of caregivers may be mainly due to educational interventions focused on knowledge of the disease with a particular attention directed toward emotional support and individual needs.
69 对阿尔茨海默病患者及其主要照顾者进行了为期 1 年的随访，以评估患者的认知（简易精神状态检查）、功能（日常生活活动工具）和行为（神经精神问卷）下降情况，同时评估照顾者的负担（照顾者负担量表）、压力（相对压力量表）、焦虑（状态-特质焦虑量表 Y）和抑郁（贝克抑郁量表）。观察 1 年后，患者的认知和功能评分恶化，而行为问题保持不变且相对较轻。1 年后，照顾者的焦虑和抑郁量表评分显著下降，而压力评分保持不变，负担略有增加。我们认为，照顾者心理状况的意外改善可能主要归因于以疾病知识为重点的教育干预，特别关注情感支持和个人需求。
