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[持续腰椎蛛网膜下腔压力监测作为所谓正常压力脑积水分流手术的指标]

[Continuous lumbar subarachnoid pressure monitoring as an indicator of shunt operation for so-called normal pressure hydrocephalus].

作者信息

Hirai O, Handa H, Kikuchi H, Ishikawa M, Kinuta Y

机构信息

Department of Neurosurgery, Hamamatsu Rosai Hospital.

出版信息

No Shinkei Geka. 1988 Sep;16(10):1141-7.

PMID:3205357
Abstract

Lumbar subarachnoid pressure (LSP) was continuously monitored via intrathecally introduced polyethylene catheter to select the patients for shunt operation. A total of seventy cases included so-called normal pressure hydrocephalus (NPH) secondary to subarachnoid hemorrhage (SAH; 34 cases), idiopathic NPH (17 cases), secondary NPH whose symptoms developed after operations for brain tumors, head injuries or meningitis (12 cases) and other intracranial diseases including pseudotumor cerebri or meningeal carcinomatosis, etc. (7 cases). Shunt operation was effective in 36 cases and not effective in 9 cases, while 25 cases were not shunted since LSP was not elevated or clinical manifestations were slight. Mean values of baseline pressure and maximum pressure in shunt effective group, shunt non-effective group and non-shunted group were 14.5, 12.7, 9.0 and 29.9, 25.0, 17.9 mmHg, respectively. Statistical difference was observed between shunt effective group and non-shunted group. Frequency of pressure waves was also significantly higher in shunt effective group than in non-shunted group. Above all, measurement of LSP was regarded as useful in idiopathic NPH. However, preoperative clinical symptoms had a closer relationship to shunt response than results of LSP in post SAH patients. Complication related to this monitoring was negligible except in one case of meningitis which was easily treated by administration of antibiotics. Follow-up study also justified our selection since no further deterioration was noted in non-shunted group. The present study indicates that measurement of LSP would be useful in selecting the patients who will benefit from shunting and in eliminating unnecessary shunt operations because this simple method is easily performed at bed side without perforating the skull.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

通过鞘内插入聚乙烯导管连续监测腰蛛网膜下腔压力(LSP),以选择适合分流手术的患者。总共70例患者,包括蛛网膜下腔出血(SAH)继发的所谓正常压力脑积水(NPH,34例)、特发性NPH(17例)、脑肿瘤、头部外伤或脑膜炎手术后出现症状的继发性NPH(12例)以及其他颅内疾病,包括假性脑瘤或脑膜癌病等(7例)。分流手术36例有效,9例无效,25例因LSP未升高或临床表现轻微未进行分流。分流有效组、分流无效组和未分流组的基线压力和最大压力平均值分别为14.5、12.7、9.0和29.9、25.0、17.9 mmHg。分流有效组与未分流组之间存在统计学差异。分流有效组的压力波频率也显著高于未分流组。最重要的是,LSP测量在特发性NPH中被认为是有用的。然而,在SAH后患者中,术前临床症状与分流反应的关系比LSP结果更密切。除1例脑膜炎经抗生素治疗容易治愈外,与该监测相关的并发症可忽略不计。随访研究也证明了我们的选择是合理的,因为未分流组未发现进一步恶化。本研究表明,LSP测量有助于选择将从分流中获益的患者,并消除不必要的分流手术,因为这种简单方法可在床边轻松进行,无需开颅。(摘要截短于250字)

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