T3期直肠癌全层切片测量外侧切缘的临床病理分析
Clinicopathologic Analysis of Lateral Margin Measured by Whole-mount Section in T3 Rectal Cancer.
作者信息
Nam Soomin, Hong Youngki, Choi Yoon Jung, Kang Jung Gu
机构信息
Department of Surgery, National Health Insurance Service Ilsan Hospital, Korea, Goyang, Korea.
Department of Pathology, National Health Insurance Service Ilsan Hospital, Goyang, Korea.
出版信息
Ann Coloproctol. 2020 Jan 31. doi: 10.3393/ac.2020.01.19.1.
PURPOSE
Total mesorectal excision is a standard technique for rectal cancer. The whole-mount section can encompass the entire specimen, so it is a more appropriate for measuring circumferential margin than conventional section. We analyzed the clinical characteristics and prognosis based on lateral margins measured by whole-mount sections.
MATERIALS AND METHODS
Medical records of patients who were operated on for T3 rectal cancer from 2005 to 2015 were reviewed retrospectively. A total of 154 patients were included. The slides of the whole-mount sections were re-reviewed by a single pathologist.
RESULTS
We divided the groups according to the length of the lateral margin (LM: 1mm, 1.5mm and 2mm). There was significantly frequent lymphovascular invasion and N state was higher when LM was short in all groups. There were more micrometastasis in group LM.
目的
全直肠系膜切除术是直肠癌的标准技术。整装切片可涵盖整个标本，因此比传统切片更适合测量环周切缘。我们基于整装切片测量的侧方切缘分析了临床特征和预后。
材料与方法
回顾性分析2005年至2015年接受T3期直肠癌手术患者的病历。共纳入154例患者。由一名病理学家对整装切片的玻片进行重新评估。
结果
我们根据侧方切缘长度（LM：1mm、1.5mm和2mm）对各组进行划分。在所有组中，当侧方切缘较短时，淋巴管侵犯明显更频繁，N分期更高。侧方切缘组有更多微转移。
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