Zare Mohammad, Mehvari Habibabadi Jafar, Moein Houshang, Barekatain Majid, Basiratnia Reza, Tofangsazi Ladan
Department of Neurology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Department of Neurosurgery, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Adv Biomed Res. 2020 Jan 21;9:3. doi: 10.4103/abr.abr_25_19. eCollection 2020.
We conducted a study to evaluate the relationship between aura types and postoperative outcomes in patients with mesial temporal sclerosis (MTS) to predict the prognosis of patients, accordingly.
In this cross-sectional study, 99 patients with MTS-temporal lobe epilepsy were enrolled based on inclusion and exclusion criteria. The types of aura were evaluated, and the outcomes were categorized according to the Engel scale. Preoperative and postoperative results of patients were compared and analyzed with the Kruskal-Wallis test.
About 73.7% of patients had seizure-free after their surgeries. The most of patients ( = 81) were in Class I of Evaluating Engel criteria. About 36.3% had not experienced any aura before their seizures, and among those with aura, the most prevalent aura was abdominal aura in 29 patients (29.3%) followed by other types of aura and affective aura. Most of the patients in Class I, II, III, and IV of Engel scale had an abdominal aura, without aura, effective aura, and abdominal aura, respectively, but this difference was not statistically significant ( = 0.691).
According to this study, the type of aura cannot predict postoperative outcomes in MTS patients. More studies are needed to evaluate this relation in better-planned studies with greater sample size.
我们开展了一项研究，以评估内侧颞叶硬化症（MTS）患者的先兆类型与术后结果之间的关系，从而预测患者的预后。
在这项横断面研究中，根据纳入和排除标准招募了99例MTS型颞叶癫痫患者。评估先兆类型，并根据恩格尔量表对结果进行分类。采用Kruskal-Wallis检验对患者术前和术后的结果进行比较和分析。
约73.7%的患者术后无癫痫发作。大多数患者（n = 81）属于恩格尔评估标准的I类。约36.3%的患者在癫痫发作前未经历任何先兆，在有先兆的患者中，最常见的先兆是腹部先兆，共29例（29.3%），其次是其他类型的先兆和情感性先兆。恩格尔量表I、II、III和IV类中的大多数患者分别有腹部先兆、无先兆、有效先兆和腹部先兆，但这种差异无统计学意义（P = 0.691）。
根据本研究，先兆类型不能预测MTS患者的术后结果。需要更多的研究在样本量更大、设计更合理的研究中评估这种关系。
