Department of Radiology, BenQ Medical Center, Nanjing Medical University, 71 Hexi Avenue, Nanjing, 210019, Jiangsu, China.
Department of Radiology, Zhongshan Hospital, Fudan University, 180 Fenglin Road, Shanghai, 200032, China.
Abdom Radiol (NY). 2020 Apr;45(4):1069-1074. doi: 10.1007/s00261-019-02394-5.
The purpose of this study was to analyze inferior vena cava (IVC) obstruction in Budd-Chiari syndrome (BCS) using rapid quantitative phase-contrast (PC) magnetic resonance (MR) imaging and compare the diagnostic efficacy of PC and MR venography (MRV) to explore the clinical prospects of applying PC quantitative diagnosis in IVC obstruction in BCS.
PC quantitative data and MRV qualitative data obtained in 35 DSA-recognized inferior vena cava obstruction in BCS patients and 35 patients with liver focal lesions found in physical examination were analyzed and compared.
The areas under the ROC curve for diagnostic parameters related to PC quantitative parameters, including stroke volume, forward flow volume, absolute stroke volume, mean flux, stroke distance, mean velocity (MV), and peak velocity, were 0.7767, 0.7788, 0.7747, 0.7665, 0.9143, 0.9159, and 0.8947, respectively. The sensitivity, specificity, and accuracy of MV in the diagnosis of IVC obstruction were 88.57%, 85.71%, and 87.14%, respectively. For IVC obstruction in BCS, there was no significant difference between the diagnostic efficacy of MV (one of the quantitative parameters of PC) and that of MRV (P = 0.0768).
PC can be used to diagnose IVC obstruction in BCS and improve the understanding of hemodynamics of IVC obstruction in BCS.
本研究旨在通过快速定量相位对比（PC）磁共振成像（MR）分析布加综合征（BCS）下腔静脉（IVC）阻塞，并比较 PC 和 MR 静脉造影（MRV）的诊断效能，探讨 PC 定量诊断在下腔静脉阻塞性BCS 中的临床应用前景。
对 35 例经数字减影血管造影（DSA）证实的布加综合征下腔静脉阻塞患者和 35 例体检发现肝脏局灶性病变患者的 PC 定量数据和 MRV 定性数据进行分析和比较。
与 PC 定量参数相关的诊断参数的 ROC 曲线下面积，包括心排量、正向血流量、绝对心排量、平均流量、射血距离、平均速度（MV）和峰值速度分别为 0.7767、0.7788、0.7747、0.7665、0.9143、0.9159 和 0.8947。MV 诊断 IVC 阻塞的灵敏度、特异度和准确度分别为 88.57%、85.71%和 87.14%。对于 BCS 下腔静脉阻塞，MV（PC 的定量参数之一）与 MRV 的诊断效能无显著差异（P=0.0768）。
PC 可用于诊断 BCS 下腔静脉阻塞，并有助于加深对 BCS 下腔静脉阻塞血流动力学的理解。
