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食管浅表黏膜鳞状上皮恶性肿瘤内镜切除标本的大体评估和取材。

Macroscopic Assessment and Sampling of Endoscopic Resection Specimens for Squamous Epithelial Malignancies with Superficial Involvement of Esophagus.

机构信息

Division of Pathology, Exploratory Oncology Research & Clinical Trial Center, National Cancer Center, Kashiwa, Chiba, Japan.

Cancer Molecular Pathology of School of Medicine, Griffith University, Gold Coast, Queensland, Australia.

出版信息

Methods Mol Biol. 2020;2129:63-81. doi: 10.1007/978-1-0716-0377-2_6.

DOI:10.1007/978-1-0716-0377-2_6
PMID:32056170
Abstract

Endoscopic resection is commonly used for superficial squamous cell carcinoma or high-grade dysplasia of esophageal squamous cell carcinoma. The depth of invasion, clearance from resection margins, and other pathological parameters are important parameters to be examined. The depth of invasion by carcinoma is associated with the risk of lymph node metastases. In endoscopic resection of superficial squamous malignancies of the esophagus, proper pathological examination of the resected specimen could guide the management of the patients in terms of the need for additional treatment, including lymph node dissection, chemotherapy, and radiation therapies.

摘要

内镜下切除术常用于治疗食管鳞状细胞癌的表浅型鳞状细胞癌或高级别上皮内瘤变。浸润深度、切缘是否干净以及其他病理参数都是需要检查的重要参数。癌的浸润深度与淋巴结转移的风险相关。在内镜下切除食管浅表性鳞状恶性肿瘤时,对切除标本进行适当的病理检查有助于指导患者的治疗管理,包括是否需要进行淋巴结清扫、化疗和放疗等额外治疗。

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