School of Physical and Occupational Therapy, McGill University, 3654 Prom Sir-William-Osler, Hosmer House, Room #200, Montreal, QC, H3G 1Y5, Canada; Translational Research in Respiratory Diseases Program, Research Institute of the McGill University Health Centre, 1001 Decarie Blvd, Block E, Montreal, QC, H4A 3J1, Canada; Centre for Health Outcomes Research and Evaluation (CORE), Research Institute of the McGill University Health Centre, 5252 Boul. de Maisonneuve Ouest, Room # 3E.01, Montreal, QC, H4A 3S5, Canada.
Respiratory Division, McGill University Health Center, 1001 Decarie Blvd, Montreal, QC, H4A 3J, Canada.
Respir Med. 2020 Jan;161:105856. doi: 10.1016/j.rmed.2019.105856. Epub 2019 Dec 19.
There has been an increased interest in simple measures of physical function and muscle strength that can be used in all clinical settings to assess individuals with chronic obstructive pulmonary disease (COPD) and predict their prognosis. The main objective was to examine the prognostic value of simple measures of physical function and muscle strength in relation to exacerbation, hospitalization and mortality in individuals with COPD.
Medline, EMBASE, Cochrane and Web of Science were searched. We included prospective observational studies that examined the prognostic value of simple performed-based tests or self-reported measures of physical function or muscle strength in relation to exacerbation, hospitalization and mortality in individuals with COPD.
Seven articles met the inclusion criteria. The most commonly used tests were the handgrip strength (HGS) (n = 4) and 1-min sit-to-stand (STS) (n = 2). There were considerable variations in terms of characteristics of patients included, setting of recruitment, type of tests used, duration of follow-up and outcome measures of interest. The majority of the studies were classified as having "fair" or "poor" methodological quality.
There is a limited number of studies examining the prognostic value of simple measures of physical function and muscle strength in relation to exacerbations, hospitalizations and mortality in individuals with COPD. To date, the HGS and 1-min STS tests are the most studied tests and seem to be suitable for prognosis purposes in individuals with COPD. However, more studies with better methodological quality are needed to confirm these findings.
人们对能够在所有临床环境中用于评估慢性阻塞性肺疾病（COPD）患者并预测其预后的简单身体功能和肌肉力量测量方法产生了浓厚的兴趣。主要目的是研究简单身体功能和肌肉力量测量方法与 COPD 患者的恶化、住院和死亡之间的预后价值。
检索了 Medline、EMBASE、Cochrane 和 Web of Science。我们纳入了前瞻性观察性研究，这些研究检查了简单的基于表现的测试或自我报告的身体功能或肌肉力量测量方法与 COPD 患者的恶化、住院和死亡之间的预后价值。
有 7 篇文章符合纳入标准。最常用的测试是握力（HGS）（n=4）和 1 分钟坐立站起测试（STS）（n=2）。纳入的患者特征、招募地点、使用的测试类型、随访时间和感兴趣的结果测量指标存在很大差异。大多数研究被归类为具有“中等”或“较差”的方法学质量。
目前，评估简单身体功能和肌肉力量测量方法与 COPD 患者恶化、住院和死亡之间的预后价值的研究数量有限。迄今为止，HGS 和 1 分钟 STS 测试是研究最多的测试，似乎适合 COPD 患者的预后目的。然而，需要更多具有更好方法学质量的研究来证实这些发现。
