Department of Ophthalmology, Government Medical College, Miraj, Maharashtra, India.
Indian J Ophthalmol. 2020 Mar;68(3):538-540. doi: 10.4103/ijo.IJO_1208_19.
A 70 year old man presented with systemic signs of toxic epidermal necrolysis (TEN) following consumption of diclofenac tablets for a prodromal illness a week back. Ophthalmic evaluation showed no perception of light in both eyes along with lid edema, total corneal sloughing, and pus-filled anterior chamber. An amniotic membrane transplant was planned but within a few hours, both eyes developed panophthalmitis with restricted extraocular movements and mild proptosis and had to be eviscerated. This is perhaps the first case showing such devastating sequelae of TEN.
一位 70 岁男性,在一周前因前驱疾病服用双氯芬酸片后出现全身中毒性表皮坏死松解症(TEN)的症状。眼部评估显示双眼无光感,伴有眼睑水肿、全角膜脱落和充满脓液的前房。计划进行羊膜移植,但在数小时内,双眼均发生全眼炎,伴有眼球运动受限、轻度眼球突出,不得不进行眼内容剜除。这可能是首例显示 TEN 如此严重后果的病例。