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在预防性用药背景下重新思考决策:服用他汀类药物如何成为“正确之举”。

Rethinking decision-making in the context of preventive medication: How taking statins becomes "the right thing to do".

作者信息

Polak Louisa, Green Judith

机构信息

Faculty of Public Health and Policy, London School of Hygiene and Tropical Medicine, United Kingdom.

School of Population Health & Environmental Sciences, Faculty of Life Sciences and Medicine, King's College London, United Kingdom.

出版信息

Soc Sci Med. 2020 Feb;247:112797. doi: 10.1016/j.socscimed.2020.112797. Epub 2020 Jan 10.

DOI:10.1016/j.socscimed.2020.112797
PMID:32059130
Abstract

To understand decision-making in the context of longterm preventive medication, we explore the way "deciding" articulates with household medication practices and other everyday routines. Taking statins as a case study, we use qualitative data from interviews with 34 participants in the UK who had all been offered statins; 19 were currently taking them. Although all participants reference similar information about statins, the way they assemble and use their knowledge varies: there is a marked asymmetry between participants taking statins and those not taking them. Deliberation is a prominent feature of accounts of deciding not to take statins, but seldom visible within accounts of those taking them. Statin-takers emphasise that they have "no choice" about taking them, while non-takers stress the need to "think about it"; statin-takers' accounts prioritise biomedical tests over experiential knowledge, whereas non-takers sometimes prioritise experiential knowledge. All participants reference similar theoretical and experiential knowledge about side-effects, but whereas non-takers often use this knowledge to explain their decision to decline statins, those taking statins downplay both their own experiences and the likelihood that these are due to statins. To account for these asymmetries, we propose a model of decision-making in which deciding upon a course of action entails constructing a narrative presentation of medication use that frames it as "the right thing to do". This model helps us examine the two-way interactions between decision-making and the material practices through which regular medication gets taken, interactions often elided from accounts both of decision-making and of medication practice. In the context of longterm medication, the boundaries between "deciding" and "doing" are blurred; decision-making is situated within a web of collaborative, discursively-informed practices.

摘要

为了理解长期预防性药物治疗背景下的决策过程,我们探讨了“决策”与家庭用药习惯及其他日常活动的关联方式。以他汀类药物为例,我们使用了对34名英国参与者的访谈所得的定性数据,这些参与者都曾被建议服用他汀类药物,其中19人正在服用。尽管所有参与者都提及了关于他汀类药物的相似信息,但他们整合和运用知识的方式各不相同:服用他汀类药物的参与者与未服用者之间存在明显的不对称性。深思熟虑是决定不服用他汀类药物的叙述中的一个突出特征,但在服用者的叙述中却很少见到。服用他汀类药物的人强调他们“别无选择”只能服用,而未服用者则强调需要“考虑一下”;服用他汀类药物者的叙述将生物医学检测置于经验知识之上,而未服用者有时则将经验知识置于优先地位。所有参与者都提到了关于副作用的相似理论和经验知识,但未服用者经常用这些知识来解释他们拒绝服用他汀类药物的决定,而服用他汀类药物者则淡化自己的经历以及这些经历由他汀类药物导致的可能性。为了解释这些不对称性,我们提出了一个决策模型,在这个模型中,决定采取某种行动方案需要构建一个关于用药的叙述性表述,将其框定为“正确的做法”。这个模型有助于我们审视决策与日常服药的物质实践之间的双向互动,而这种互动在决策和用药实践的叙述中常常被忽略。在长期用药的背景下,“决策”与“行动”之间的界限是模糊的;决策存在于一个由协作性的、话语引导的实践所构成的网络之中。

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