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严重急性营养不良康复时间及其预测因素:埃塞俄比亚西北部阿姆哈拉地区的一项多中心回顾性随访研究。

Time to recovery from severe acute malnutrition and its predictors: a multicentre retrospective follow-up study in Amhara region, north-west Ethiopia.

机构信息

Department of Epidemiology and Biostatistics, Institute of Public Health, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia

Department of Epidemiology and Biostatistics, Institute of Public Health, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.

出版信息

BMJ Open. 2020 Feb 13;10(2):e034583. doi: 10.1136/bmjopen-2019-034583.

DOI:10.1136/bmjopen-2019-034583
PMID:32060161
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7045195/
Abstract

OBJECTIVES

This study aimed to determine the time to recovery from severe acute malnutrition (SAM) and its predictors in selected public health institutions in Amhara Regional State, Ethiopia.

DESIGN

An institution-based retrospective follow-up study was conducted using data extracted from 1690 patient cards from September 2012 to November 2016.

SETTING

Selected government health institutions in the Amhara region, Ethiopia.

PARTICIPANTS

Children treated in therapeutic feeding units for SAM were included.

OUTCOME MEASURES

Time to recovery from SAM.

RESULTS

One thousand and fifty children have recovered from SAM, 62.13% (95% CI 59.8% to 64.5%). The median time to recovery was 16 days (IQR=11-28). Female gender (adjusted HR (AHR)=0.81, 95% CI 0.67 to 0.98), oedematous malnutrition (AHR=0.74 95% CI 0.59 to 0.93), pneumonia (AHR=0.66, 95% CI 0.53 to 0.83), tuberculosis (AHR=0.53, 95% CI 0.36 to 0.77), HIV/AIDS (AHR=0.47, 95% CI 0.28 to 0.79), anaemia (AHR=0.73, 95% CI 0.60 to 0.89) and receiving vitamin A (AHR=1.43, 95% CI 1.12 to 1.82) were notably associated with time to recovery.

CONCLUSIONS

The time to recovery in this study was acceptable but the proportion of recovery was far below the minimum standard. Special emphasis should be given to the prevention and treatment of comorbidities besides the therapeutic feeding. Supplementing vitamin A would also help to improve the recovery rate.

摘要

目的

本研究旨在确定在埃塞俄比亚阿姆哈拉地区选定的公立卫生机构中,严重急性营养不良(SAM)的恢复时间及其预测因素。

设计

这是一项基于机构的回顾性随访研究,使用了 2012 年 9 月至 2016 年 11 月期间从 1690 张患者卡片中提取的数据。

地点

埃塞俄比亚阿姆哈拉地区选定的政府卫生机构。

参与者

纳入在治疗性喂养单位接受 SAM 治疗的儿童。

结局指标

从 SAM 中恢复的时间。

结果

1050 名儿童从 SAM 中康复,占 62.13%(95%CI 59.8%至 64.5%)。中位恢复时间为 16 天(IQR=11-28)。女性(校正 HR(AHR)=0.81,95%CI 0.67 至 0.98)、水肿性营养不良(AHR=0.74,95%CI 0.59 至 0.93)、肺炎(AHR=0.66,95%CI 0.53 至 0.83)、结核病(AHR=0.53,95%CI 0.36 至 0.77)、艾滋病毒/艾滋病(AHR=0.47,95%CI 0.28 至 0.79)、贫血(AHR=0.73,95%CI 0.60 至 0.89)和接受维生素 A(AHR=1.43,95%CI 1.12 至 1.82)与恢复时间显著相关。

结论

本研究的恢复时间是可以接受的,但恢复比例远低于最低标准。除了治疗性喂养外,还应特别重视合并症的预防和治疗。补充维生素 A 也有助于提高恢复率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/08cb/7045195/4f396db6ee2c/bmjopen-2019-034583f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/08cb/7045195/4f396db6ee2c/bmjopen-2019-034583f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/08cb/7045195/4f396db6ee2c/bmjopen-2019-034583f01.jpg

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