Department of Biology, Skidmore College, Saratoga Springs, NY, United States.
Vitam Horm. 2020;112:265-287. doi: 10.1016/bs.vh.2019.10.002. Epub 2019 Nov 8.
Comparative studies over the last two decades have revealed that fishes leverage aquaporins (AQPs) to facilitate the movements of water, small non-ionic solutes, and gases across cell membranes. Accordingly, AQPs are expressed in tissues responsible for maintaining hydromineral balance of the whole organism. In teleost fishes, threats to hydromineral balance imposed by fluctuations in environmental salinity are met with the activation of multiple endocrine axes. This chapter first discusses recent advances in our understanding of how hormones control the expression of AQPs in tissues that support hydromineral balance, namely the gastrointestinal tract, kidney, and gill. The second objective of this chapter is to review how hormones regulate teleost AQPs in support of fluid transport processes underlying the production of gametes specialized for release into aquatic environments.
在过去的二十年中，比较研究揭示了鱼类利用水通道蛋白（AQP）来促进水、小非离子溶质和气体穿过细胞膜的运动。因此，AQP 在负责维持整个生物体水盐平衡的组织中表达。在硬骨鱼类中，环境盐度波动对水盐平衡造成的威胁，通过激活多个内分泌轴来应对。本章首先讨论了我们对激素如何控制支持水盐平衡的组织中 AQP 表达的理解的最新进展，即胃肠道、肾脏和鳃。本章的第二个目标是回顾激素如何调节硬骨鱼 AQP，以支持配子产生的液体运输过程，这些配子专门释放到水生环境中。
