College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, China.
College of Ethnomedicine, Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, China.
Pharmacol Res. 2020 May;155:104688. doi: 10.1016/j.phrs.2020.104688. Epub 2020 Feb 13.
Tibetan medicine (TM), the second largest traditional Chinese medicine system in China, boasts a long history and an integrated theoretical system. It abounds with classical medical works constituing a unique corpus of Tibetan materia medica (TMM). China has now conceived a modern education system of TM, and Tibetan medical hospitals at different levels have been set up. Many enterprises are granted the privileges to produce preparations of TM in compliance with Good Manufacturing Practices (GMP) regulations. However, there still exist unsolved issuess in TMM research as to the mechanism of action and the active constituents of TMM which are now been tackled through pharmacology and modern science and technology. Up till now, the mechanism of action and the active constituents of 141 medicines as well as 230 preparations of TM have been preliminarily revealed. This paper reviews in detail the development of TM and the status quo of TM's pharmacological research, in hope of serving a reference value for the promotion of the modernization of TM and understanding of TM among the medical scholars.
藏医药（TM）是中国第二大传统中医药体系，拥有悠久的历史和完整的理论体系。它拥有丰富的经典医学著作，构成了独特的藏药体系（TMM）。中国现在已经构思了藏医药的现代教育体系，建立了不同层次的藏医院。许多企业被授予了按照良好生产规范（GMP）生产藏药制剂的特权。然而，TMM 的作用机制和有效成分仍然存在尚未解决的问题，目前正在通过药理学和现代科学技术来解决。到目前为止，已经初步揭示了 141 种药物和 230 种藏药制剂的作用机制和有效成分。本文详细回顾了藏医药的发展和藏医药药理学研究的现状，希望为促进藏医药的现代化和医学学者对藏医药的理解提供参考价值。
