细胞模型系统中的静止成纤维细胞。
Quiescent fibroblasts in a cellular model system.
作者信息
Kristensen S R, Petersen P H
机构信息
Department of Clinical Chemistry, Odense University Hospital, Denmark.
出版信息
Scand J Clin Lab Invest. 1988 Sep;48(5):413-7. doi: 10.1080/00365518809085750.
PMID:3206188
Abstract
Quiescent fibroblasts are non-dividing cells in a reversible postmitotic state induced by lowering the serum concentration of the medium (e.g. from 10% to 0.3%). Three to seven days after lowering the serum concentration only minor metabolic changes will take place in the cells. During this period the quiescent fibroblasts can be used experimentally in a model system for various periods of time.
摘要
静止的成纤维细胞是通过降低培养基血清浓度（例如从10%降至0.3%）诱导进入可逆的有丝分裂后状态的非分裂细胞。降低血清浓度三到七天后，细胞仅会发生轻微的代谢变化。在此期间，静止的成纤维细胞可在模型系统中用于不同时间段的实验。
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