Yan X F, Yang J W, Bai X K, Wang H R, Feng F, Hou L L, Sun Y, Wang W J, Li X
National Clinical Research Center for Cardiovascular Diseases, State Key Laboratory of Cardiovascular Disease, National Center for Cardiovascular Diseases, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China.
Cardiovascular Institute of Luohe, Luohe Central Hospital, the First Affiliated Hospital, Luohe Medical College, Luohe 462000, China.
Zhonghua Liu Xing Bing Xue Za Zhi. 2020 Jan 10;41(1):68-73. doi: 10.3760/cma.j.issn.0254-6450.2020.01.013.
To understand the awareness, treatment, and control of hypertension in residents aged 35-75 years in eastern China, analyze the treatment mode for antihypertensive agents while identifying those factors affecting awareness, treatment and control. The data collected in eastern China from the China Patient-Centered Evaluative Assessment of Cardiac Events (PEACE) Million Persons Project were used to obtain the information about the awareness, treatment and control of hypertension in the residents and the antihypertensive medication treatment mode in this area. Multilevel mixed-effects model was used to explore the association of the demographic characteristics of hypertension patients with the rates of awareness, treatment and control of hypertension. A total of 640 539 participants aged 35-75 years, mean age (56.9±9.6) years, were included in the analysis, women accounted for 59.7 and 318 741 (49.8) of the participants suffered from hypertension. Among those hypertensive patients, 46.5 were aware of their condition, 38.1 were taking prescribed antihypertensive medications, and 11.1 had achieved the control of hypertension, the differences were significant among provinces, between urban area and rural area and among different demographical groups. Calcium-channel blockers was the most commonly used medication (45.1), and 78 735 hypertension patients (86.2) took only one type of medication. Older age, higher household income, higher level of education, and histories of myocardial infarction, stroke and diabetes were associated with higher awareness, treatment and control of hypertension (<0.05). The rates of awareness, treatment and control of hypertension were low in residents in eastern China. The differences in hypertension management were significant among provinces and between urban area and rural area. Further efforts are needed to enhance the system of hypertension prevention, screening, diagnosis and treatment.
为了解中国东部35 - 75岁居民高血压的知晓率、治疗率和控制率，分析抗高血压药物的治疗模式，并识别影响知晓、治疗和控制的因素。利用中国心脏事件以患者为中心的评估（PEACE）百万人项目在中国东部收集的数据，获取该地区居民高血压的知晓、治疗和控制情况以及抗高血压药物治疗模式的信息。采用多水平混合效应模型探讨高血压患者人口统计学特征与高血压知晓率、治疗率和控制率之间的关联。共有640539名年龄在35 - 75岁之间的参与者纳入分析，平均年龄（56.9±9.6）岁，女性占59.7%，其中318741名（49.8%）参与者患有高血压。在这些高血压患者中，46.5%知晓自己的病情，38.1%正在服用规定的抗高血压药物，11.1%实现了高血压的控制，各省之间、城乡之间以及不同人口群体之间的差异均有统计学意义。钙通道阻滞剂是最常用的药物（45.1%），78735名高血压患者（86.2%）仅服用一种药物。年龄较大、家庭收入较高、教育水平较高以及有心肌梗死、中风和糖尿病病史与高血压的较高知晓率、治疗率和控制率相关（<0.05）。中国东部居民高血压的知晓率、治疗率和控制率较低。高血压管理在各省之间以及城乡之间存在显著差异。需要进一步努力加强高血压预防、筛查、诊断和治疗体系。
