Division of Interventional Radiology and Image Guided Medicine, Department of Radiology and Imaging Sciences, Emory University School of Medicine, Atlanta, GA, USA.
Can Assoc Radiol J. 2020 Feb;71(1):75-80. doi: 10.1177/0846537119888391. Epub 2020 Jan 27.
Uterine artery embolization (UAE) is an effective treatment for the management of symptomatic uterine fibroids. We aim to evaluate the efficacy of superior hypogastric nerve block (SHNB) in reducing narcotic analgesia use for postprocedural pain after UAE.
A retrospective review of 88 consecutive patients with symptomatic fibroids who underwent UAE between August 2015 and August 2018 was performed. A total of 44 patients had intraprocedural SHNB and 44 patients had no SHNB. They were placed on a morphine patient-controlled anesthesia (PCA) pump after the procedure and were admitted for overnight observation. The total amount of PCA narcotic analgesia received was recorded for each patient. Additional factors including fibroid size, fibroid location, and patient age were evaluated to determine the predictors of narcotic use reduction after SHNB.
The mean amount of postprocedural morphine use was 51.7 mg in patients who did not receive an SHNB versus 35.9 mg in patients who did receive an SHNB ( = .008), resulting in a 47.2% reduction in narcotic analgesia use in the SHNB cohort. A significant reduction in morphine use with SHNB was associated with fibroid size greater than 5 cm ( = .009), intramural fibroid location ( = .04), and patients 45 years or younger ( = .006).
The use of SHNB could significantly reduce the amount of narcotic analgesia required for pain control after UAE with larger intramural fibroids and younger patients as predictors of increased efficacy.
子宫动脉栓塞术(UAE)是治疗有症状子宫肌瘤的有效方法。我们旨在评估下腹下神经阻滞(SHNB)在减少 UAE 后程序性疼痛的阿片类药物镇痛使用的效果。
回顾性分析了 2015 年 8 月至 2018 年 8 月期间接受 UAE 的 88 例有症状子宫肌瘤患者。44 例患者术中进行了 SHNB,44 例患者未进行 SHNB。手术后,他们都被安置在吗啡病人自控麻醉(PCA)泵上,并接受过夜观察。记录每位患者接受的 PCA 阿片类镇痛药的总用量。评估了肌瘤大小、肌瘤位置和患者年龄等其他因素,以确定 SHNB 后减少阿片类药物使用的预测因素。
未接受 SHNB 的患者术后吗啡用量的平均值为 51.7mg,而接受 SHNB 的患者为 35.9mg( =.008),SHNB 组的阿片类药物镇痛用量减少了 47.2%。SHNB 与肌瘤大小大于 5cm( =.009)、壁内肌瘤位置( =.04)和 45 岁或以下的患者( =.006)相关,与吗啡用量的显著减少相关。
SHNB 的使用可以显著减少 UAE 后疼痛控制所需的阿片类药物用量,并且较大的壁内肌瘤和年轻患者是增加疗效的预测因素。