Department of Preventive Medicine Northwestern University Feinberg School of Medicine Chicago IL.
Division of Cardiology Department of Pediatrics Ann & Robert H. Lurie Children's Hospital of Chicago Northwestern University Feinberg School of Medicine Chicago IL.
J Am Heart Assoc. 2020 Feb 18;9(4):e015123. doi: 10.1161/JAHA.119.015123. Epub 2020 Feb 17.
Background Pregnancy is a cardiometabolic stressor and thus a critical period to address women's lifetime cardiovascular health (CVH). However, CVH among US pregnant women has not been characterized. Methods and Results We analyzed cross-sectional data from National Health and Nutrition Examination Surveys 1999 to 2014 for 1117 pregnant and 8200 nonpregnant women, aged 20 to 44 years. We assessed 7 CVH metrics using American Heart Association definitions modified for pregnancy; categorized metrics as ideal, intermediate, or poor; assigned these categories 2, 1, or 0 points, respectively; and summed across the 7 metrics for a total score of 0 to 14 points. Total scores 12 to 14 indicated high CVH; 8 to 11, moderate CVH; and 0 to 7, low CVH. We applied survey weights to generate US population-level estimates of CVH levels and compared pregnant and nonpregnant women using demographic-adjusted polytomous logistic and linear regression. Among pregnant women, the prevalences (95% CIs) of ideal levels of CVH metrics were 0.1% (0%-0.3%) for diet, 27.3% (22.2%-32.3%) for physical activity, 38.9% (33.7%-44.0%) for total cholesterol, 51.1% (46.0%-56.2%) for body mass index, 77.7% (73.3%-82.2%) for smoking, 90.4% (87.5%-93.3%) for blood pressure, and 91.6% (88.3%-94.9%) for fasting glucose. The mean total CVH score was 8.3 (95% CI, 8.0-8.7) of 14, with high CVH in 4.6% (95% CI, 0.5%-8.8%), moderate CVH in 60.6% (95% CI, 52.3%-68.9%), and low CVH in 34.8% (95% CI, 26.4%-43.2%). CVH levels were significantly lower among pregnant versus nonpregnant women; for example, 13.0% (95% CI, 11.0%-15.0%) of nonpregnant women had high CVH (adjusted, comparison =0.01). Conclusions From 1999 to 2014, <1 in 10 US pregnant women, aged 20 to 44 years, had high CVH.
妊娠是一种心脏代谢应激源,因此是解决女性终生心血管健康(CVH)的关键时期。然而,美国孕妇的 CVH 尚未得到描述。
我们分析了 1999 年至 2014 年全国健康和营养调查中 1117 名孕妇和 8200 名非孕妇的数据,年龄在 20 至 44 岁之间。我们使用美国心脏协会为妊娠修改的定义评估了 7 项 CVH 指标;将指标分类为理想、中等或差;分别为每个指标分配 2、1 或 0 分;并根据 7 项指标的总分计算,总分为 0 至 14 分。总分 12 至 14 分表示 CVH 高;8 至 11 分表示 CVH 中等;0 至 7 分表示 CVH 低。我们应用调查权重生成 CVH 水平的美国人群水平估计,并使用人口统计学调整的多项逻辑回归和线性回归比较孕妇和非孕妇。在孕妇中,CVH 指标理想水平的流行率(95%CI)分别为:饮食 0.1%(0%-0.3%)、体力活动 27.3%(22.2%-32.3%)、总胆固醇 38.9%(33.7%-44.0%)、身体质量指数 51.1%(46.0%-56.2%)、吸烟 77.7%(73.3%-82.2%)、血压 90.4%(87.5%-93.3%)和空腹血糖 91.6%(88.3%-94.9%)。总 CVH 评分平均为 14 分中的 8.3 分(95%CI,8.0-8.7),高 CVH 占 4.6%(95%CI,0.5%-8.8%),中等 CVH 占 60.6%(95%CI,52.3%-68.9%),低 CVH 占 34.8%(95%CI,26.4%-43.2%)。与非孕妇相比,孕妇的 CVH 水平明显较低;例如,13.0%(95%CI,11.0%-15.0%)的非孕妇具有高 CVH(调整后,比较=0.01)。
1999 年至 2014 年,美国年龄在 20 至 44 岁之间的孕妇中,不到 10%的孕妇具有高 CVH。