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体外膜肺氧合转运对急性呼吸窘迫综合征患者短期和长期生存的影响。

Effect of extracorporeal membrane oxygenation transport on short- and long-term survival in patients with acute respiratory distress syndrome.

作者信息

Steimer Desiree A, Hernandez Omar, Ogola Gerald, Mason David P, Schwartz Gary S

机构信息

Department of Thoracic Surgery, Brigham and Women's HospitalBostonMassachusetts.

Department of Perfusion Services, Baylor University Medical CenterDallasTexas.

出版信息

Proc (Bayl Univ Med Cent). 2019 Oct 25;33(1):5-9. doi: 10.1080/08998280.2019.1669120. eCollection 2020 Jan.

DOI:10.1080/08998280.2019.1669120
PMID:32063755
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6988654/
Abstract

Venovenous extracorporeal membrane oxygenation (ECMO) has emerged as an important tool in the treatment of acute respiratory distress syndrome (ARDS). The creation of portable ECMO circuits and pumps has supported the development of interfacility ECMO programs. Prior studies have demonstrated that ECMO transport is safe; however, long-term outcomes for these patients remain unknown. Retrospective analysis of our 5-year experience identified 58 patients transported on ECMO and 82 patients cannulated at our institution. When short-term (30 days) and long-term (1 year) outcomes were compared between these cohorts, there was no statistically significant difference in survival ( = 0.44 and 0.49). There were no deaths related to transport, and the rate of ECMO-related complications was similar between the groups. With established patient safety and similar long-term survival, ECMO transport is a feasible solution to provide access to ECMO for all communities.

摘要

静脉-静脉体外膜肺氧合(ECMO)已成为治疗急性呼吸窘迫综合征(ARDS)的一项重要工具。便携式ECMO回路和泵的出现推动了院际ECMO项目的发展。既往研究表明,ECMO转运是安全的;然而,这些患者的长期预后仍不明确。对我们5年经验的回顾性分析确定了58例接受ECMO转运的患者以及82例在我们机构进行插管的患者。当比较这些队列的短期(30天)和长期(1年)预后时,生存率无统计学显著差异(P = 0.44和0.49)。没有与转运相关的死亡,两组之间ECMO相关并发症的发生率相似。鉴于已确立的患者安全性和相似的长期生存率,ECMO转运是为所有社区提供ECMO治疗机会的可行解决方案。

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J Cardiothorac Vasc Anesth. 2022 Jun;36(6):1703-1708. doi: 10.1053/j.jvca.2021.09.029. Epub 2021 Sep 24.
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Safety of Interhospital ECMO Transport by Low-Volume ECMO Transport Centers.低容量体外膜肺氧合转运中心进行院际体外膜肺氧合转运的安全性
J Pediatr Intensive Care. 2021 Jun;10(2):126-132. doi: 10.1055/s-0040-1714706. Epub 2020 Jul 30.

本文引用的文献

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Timing of ECMO Initiation Impacts Survival in Influenza-Associated ARDS.体外膜肺氧合(ECMO)启动时机对流感相关急性呼吸窘迫综合征(ARDS)患者的生存有影响。
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One Hundred Transports on Extracorporeal Support to an Extracorporeal Membrane Oxygenation Center.100例体外支持转运至体外膜肺氧合中心
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5
Two decades' experience with interfacility transport on extracorporeal membrane oxygenation.体外膜肺氧合技术下医疗机构间转运的二十年经验
Ann Thorac Surg. 2014 Oct;98(4):1363-70. doi: 10.1016/j.athoracsur.2014.06.025. Epub 2014 Aug 20.
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Extracorporeal membrane oxygenation for ARDS in adults.体外膜肺氧合在成人急性呼吸窘迫综合征中的应用。
N Engl J Med. 2011 Nov 17;365(20):1905-14. doi: 10.1056/NEJMct1103720.
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Safe transport of critically ill adult patients on extracorporeal membrane oxygenation support to a regional extracorporeal membrane oxygenation center.危重症成人患者在体外膜肺氧合支持下安全转运至区域体外膜肺氧合中心。
ASAIO J. 2011 Sep-Oct;57(5):421-5. doi: 10.1097/MAT.0b013e3182238b55.
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First experience with the ultra compact mobile extracorporeal membrane oxygenation system Cardiohelp in interhospital transport.超紧凑型移动体外膜肺氧合系统Cardiohelp用于院际转运的首次体验。
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