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本文引用的文献

1
The prognostic role of neutrophil-lymphocyte ratio and platelet-lymphocyte ratio in patients with stage III non-small cell lung cancer treated with concurrent chemoradiotherapy.中性粒细胞与淋巴细胞比值及血小板与淋巴细胞比值在接受同步放化疗的Ⅲ期非小细胞肺癌患者中的预后作用
Indian J Cancer. 2018 Jul-Sep;55(3):276-281. doi: 10.4103/ijc.IJC_624_17.
2
Neutrophil-lymphocyte ratio, platelet-lymphocyte ratio and mean platelet volume in Japanese patients with psoriasis and psoriatic arthritis: Response to therapy with biologics.中性粒细胞-淋巴细胞比值、血小板-淋巴细胞比值和平均血小板体积在日本银屑病和银屑病关节炎患者中的变化:生物制剂治疗的反应。
J Dermatol. 2017 Oct;44(10):1112-1121. doi: 10.1111/1346-8138.13875. Epub 2017 May 11.
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[Measles outbreak in the adult age group: evaluation of 28 cases].[成人年龄组中的麻疹暴发:28例病例评估]
Mikrobiyol Bul. 2016 Jan;50(1):112-21. doi: 10.5578/mb.10692.
4
Clinical and laboratory features of adult measles cases detected in Van, Turkey.
J Pak Med Assoc. 2015 Mar;65(3):273-6.
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Changes in platelet count and mean platelet volume during infectious and inflammatory disease and their correlation with ESR and CRP.感染性和炎症性疾病期间血小板计数和平均血小板体积的变化及其与血沉(ESR)和C反应蛋白(CRP)的相关性。
J Clin Lab Anal. 2014 May;28(3):245-8. doi: 10.1002/jcla.21673. Epub 2014 Jan 29.
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Neutrophil recruitment and function in health and inflammation.中性粒细胞在健康与炎症中的募集与功能。
Nat Rev Immunol. 2013 Mar;13(3):159-75. doi: 10.1038/nri3399.
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Immunity, inflammation, and cancer.免疫、炎症与癌症。
Cell. 2010 Mar 19;140(6):883-99. doi: 10.1016/j.cell.2010.01.025.
8
Mean platelet volume predicts early death in acute pulmonary embolism.平均血小板体积可预测急性肺栓塞患者的早期死亡。
Heart. 2010 Mar;96(6):460-5. doi: 10.1136/hrt.2009.180489. Epub 2009 Nov 11.
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Measles is still a cause for concern in Europe.麻疹在欧洲仍然令人担忧。
Euro Surveill. 2008 Apr 17;13(16):18837.
10
Measles in the United Kingdom: can we eradicate it by 2010?英国的麻疹:我们能在2010年前根除它吗?
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麻疹患者的中性粒细胞/淋巴细胞比值、血小板/淋巴细胞比值及平均血小板体积值

Neutrophil/Lymphocyte Ratios, Platelet/Lymphocyte Ratios, and Mean Platelet Volume Values in Patients with Measles.

作者信息

Solmaz Abdullah, Demir Abit, Gümüş Hüseyin, Aksoy Mustafa, Solmaz Filiz

机构信息

Pediatrics, Harran University, Şanlıurfa, TUR.

Dermatology, Harran University, Şanlıurfa, TUR.

出版信息

Cureus. 2020 Jan 9;12(1):e6607. doi: 10.7759/cureus.6607.

DOI:10.7759/cureus.6607
PMID:32064188
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7008753/
Abstract

AIM

The purpose of this study was to compare neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio (PLR), and mean platelet volume (MPV) values of patients with measles within the healthy control group and then determine the utility of these parameters for determination of inflammatory situation in patients with measles.

MATERIALS AND METHOD

A total of 51 pediatric patients who had visited Harran University Medical Faculty Pediatrics Clinic between June 2018 and May 2019 and who had been diagnosed with measles after anamnesis, clinical, and serological evaluations were included our study; 49 healthy children who visited our clinic for various reasons and had taken hemogram tests were also added to our study as the control group.

RESULTS

NLR and PLR values were observed higher than the control group for patients diagnosed with measles; however, the difference between the two groups was not statistically significant (p values 0.515 and 0.796, respectively). When MPV values of patients diagnosed with measles and control groups were compared, it was determined that MPV value was statistically lower in patients diagnosed with measles (p: 0.001).

CONCLUSION

Based on the parameters obtained through our study, it can be said that NLR and PLR are not suitable parameters for proving inflammation in patients with measles but MPV can be used as a convenient parameter for that purpose. However, prospective studies conducted with more patients are needed in this respect.

摘要

目的

本研究旨在比较麻疹患者与健康对照组中性粒细胞/淋巴细胞比值(NLR)、血小板/淋巴细胞比值(PLR)及平均血小板体积(MPV)值,进而确定这些参数在判定麻疹患者炎症状况方面的效用。

材料与方法

纳入2018年6月至2019年5月期间前往哈兰大学医学院儿科门诊就诊、经问诊、临床及血清学评估后确诊为麻疹的51例儿科患者;另外,将因各种原因前来我院门诊就诊并进行血常规检查的49例健康儿童作为对照组纳入本研究。

结果

确诊为麻疹的患者NLR和PLR值高于对照组;然而,两组间差异无统计学意义(p值分别为0.515和0.796)。比较确诊为麻疹的患者与对照组的MPV值,发现确诊为麻疹的患者MPV值在统计学上较低(p:0.001)。

结论

基于本研究获得的参数,可以说NLR和PLR并非证明麻疹患者炎症的合适参数,但MPV可作为用于此目的的便捷参数。然而,在这方面需要对更多患者进行前瞻性研究。