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一例由甲酸和硫酸混合物导致的罕见一氧化碳中毒病例。

An Unusual Case of Carbon Monoxide Poisoning from Formic and Sulfuric Acid Mixture.

作者信息

Ershad Muhammed, Melisiotis Athanasios, Gaskill Zachary, Kelly Matthew, Hamilton Richard

机构信息

Drexel University College of Medicine, Department of Emergency Medicine, Division of Medical Toxicology, Philadelphia, Pennsylvania.

Drexel University College of Medicine, Department of Emergency Medicine, Philadelphia, Pennsylvania.

出版信息

Clin Pract Cases Emerg Med. 2019 Dec 17;4(1):51-54. doi: 10.5811/cpcem.2019.10.44265. eCollection 2020 Feb.

DOI:10.5811/cpcem.2019.10.44265
PMID:32064425
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7012551/
Abstract

Formic acid, when combined with sulfuric acid, gets dehydrated to form carbon monoxide (CO). A 27-year-old female was found unconscious inside a car, next to a container with a mixture of sulfuric acid and formic acid. Concentrations of up to 400 parts per million of CO were measured inside the car post ventilation. Serum carboxyhemoglobin level was 15% after receiving 100% oxygen for two hours. The patient received hyperbaric oxygen therapy after which she was extubated with normal mental status. On follow-up after three months, she demonstrated neurocognitive abnormalities suggestive of delayed neurological sequelae from CO exposure.

摘要

甲酸与硫酸混合时会脱水形成一氧化碳(CO)。一名27岁女性被发现昏迷在一辆汽车内,旁边有一个装有硫酸和甲酸混合物的容器。通风后,车内测得的一氧化碳浓度高达百万分之400。在接受两小时100%氧气治疗后,血清碳氧血红蛋白水平为15%。患者接受了高压氧治疗,之后拔管,精神状态正常。三个月后的随访中,她出现了神经认知异常,提示一氧化碳暴露导致了迟发性神经后遗症。

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本文引用的文献

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Clinical Policy: Critical Issues in the Evaluation and Management of Adult Patients Presenting to the Emergency Department With Acute Carbon Monoxide Poisoning.临床政策:急诊科成年急性一氧化碳中毒患者评估与管理的关键问题
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Carbon monoxide poisoning and pulmonary injury from the mixture of formic and sulfuric acids.一氧化碳中毒以及甲酸与硫酸混合物导致的肺损伤。
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Clin Toxicol (Phila). 2008 Apr;46(4):287-9. doi: 10.1080/15563650701378746.
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A suicide using a homemade carbon monoxide "death machine".一起使用自制一氧化碳“死亡机器”的自杀事件。
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