Department of Radiology, The First Affiliated Hospital of Nanjing Medical University, No. 300 Guangzhou Road, Gulou district, Nanjing, Jiangsu Province, China.
MR Collaboration, Siemens Healthcare Ltd., Shanghai, China.
Eur Radiol. 2020 Jun;30(6):3059-3065. doi: 10.1007/s00330-020-06682-3. Epub 2020 Feb 17.
We aimed to investigate the utility of compressed sensing time-of-flight magnetic resonance angiography (CS TOF-MRA) for diagnosing intracranial and cervical arterial stenosis by using digital subtraction angiography (DSA) as the reference standard.
Thirty-seven patients with head and neck arterial stenoses who underwent CS TOF-MRA and DSA were retrospectively enrolled. The reconstructed resolution of CS TOF-MRA was 0.4 × 0.4 × 0.4 mm. The scan time was 5 min and 2 s. The image quality of CS TOF-MRA was independently ranked by two neuroradiologists in 1031 arterial segments. The luminal stenosis grades on CS TOF-MRA and DSA were analyzed in 61 arterial segments and were compared using the Wilcoxon signed-rank test. The ability of CS TOF-MRA to predict moderate to severe stenosis or occlusion was analyzed.
The image quality of most arterial segments (95.2%) on CS TOF-MRA was excellent. Arterial segments with low image quality were mainly the V3-4 segments of the vertebral artery. The majority of arterial stenoses (62.3%) were located in the cervical internal carotid artery. The luminal stenosis grades of CS TOF-MRA were concordant with that of DSA in 50 of 61 segments (p = 0.366). CS TOF-MRA had a sensitivity of 84.4% and a specificity of 88.5% for predicting moderate to severe stenosis. For detecting occlusion lesions, it had a sensitivity of 100% and a specificity of 94.1%.
CS TOF-MRA provides adequate image quality within a reasonable acquisition time and is a reliable tool for diagnosing head and neck arterial steno-occlusive disease.
• CS TOF-MRA provides a relatively large coverage (16 cm), high resolution (0.4 × 0.4 × 0.4 mm) and good image quality of head and neck arteries within 5 min and 2 s. • The diagnostic accuracy of CS TOF-MRA in the assessment of moderate to severe stenosis and occlusion was comparable with that of DSA. • Arterial segments with low image quality were mainly the V3 and V4 segments of the vertebral artery.
我们旨在通过数字减影血管造影（DSA）作为参考标准，研究压缩感知时间飞跃磁共振血管造影（CS TOF-MRA）在诊断颅内和颈内动脉狭窄中的应用。
回顾性纳入 37 例头颈部动脉狭窄患者，行 CS TOF-MRA 和 DSA 检查。CS TOF-MRA 的重建分辨率为 0.4×0.4×0.4mm，扫描时间为 5 分 2 秒。由两位神经放射科医生对 1031 个动脉节段的 CS TOF-MRA 图像质量进行独立评分。分析 61 个动脉节段的 CS TOF-MRA 和 DSA 的管腔狭窄程度，并采用 Wilcoxon 符号秩检验进行比较。分析 CS TOF-MRA 预测中度至重度狭窄或闭塞的能力。
CS TOF-MRA 大部分动脉节段（95.2%）的图像质量良好。图像质量较差的动脉节段主要为椎动脉 V3-4 段。大多数动脉狭窄（62.3%）位于颈内动脉。61 个节段中，50 个节段的管腔狭窄程度 CS TOF-MRA 与 DSA 一致（p=0.366）。CS TOF-MRA 预测中度至重度狭窄的敏感性为 84.4%，特异性为 88.5%。对于检测闭塞性病变，其敏感性为 100%，特异性为 94.1%。
CS TOF-MRA 在合理的采集时间内提供了足够的图像质量，是一种可靠的诊断头颈部动脉狭窄闭塞性疾病的工具。
• CS TOF-MRA 在 5 分 2 秒内提供了相对较大的覆盖范围（16cm）、高分辨率（0.4×0.4×0.4mm）和良好的头颈部动脉图像质量。
• CS TOF-MRA 评估中度至重度狭窄和闭塞的诊断准确性与 DSA 相当。
• 图像质量较差的动脉节段主要为椎动脉 V3 和 V4 段。
