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胃切除术后 5 年的胃容量与体重减轻的相关性。

Correlation of Gastric Volume and Weight Loss 5 Years Following Sleeve Gastrectomy.

机构信息

Bariatric and Metabolic Surgery Unit, Section of Gastrointestinal Surgery, Hospital del Mar, Barcelona, Spain.

Hospital del Mar Medical Research Institute (IMIM), Barcelona, Spain.

出版信息

Obes Surg. 2020 Jun;30(6):2199-2205. doi: 10.1007/s11695-020-04445-z.

Abstract

INTRODUCTION

The volume of the gastric reservoir (VGR) after sleeve gastrectomy influences weight loss in the short-term, but long-term results are scarce. The aim was to analyze the correlation between the VGR and weight loss at 5 years of follow-up.

METHODS

It is a prospective observational study of 50 patients undergoing sleeve gastrectomy (SG) from February 2009 to December 2013. An upper gastrointestinal series was performed at 1 month and at 1 and 5 years after surgery. A composite formula was used for VGR estimation. Weight loss-related data included the following: body mass index (BMI), percentage of excess weight loss (%EWL), and percentage of excess BMI loss (%EBMIL) at 1 month and at 1 and 5 years. Uni- and multivariate analyses were carried out to determine other factors that might influence long-term weight loss results.

RESULTS

The %EWL at 1 year was 74.5(63.8-86) vs. 55.5(47-74.3) at 5 years (p < 0.001). The VGR 1 month after surgery was 114.9 (90.5-168.3) mL. The VGR increased from 216.7 (155.1-278.6) to 367.5 (273-560.3) mL (p < 0.001) at 1 and 5 years. Although a significant inverse correlation was observed between VGR and BMI, %EWL, and %EBMIL at 1 year, it disappeared at 5 years. In the multivariate analysis, the main factor to predict worse weight results at 5 years was a pre-surgical BMI ≥ 50 kg/m.

CONCLUSION

The VGR increased progressively during the study period. Although an inverse relationship between VGR and weight was found at 1 year, this correlation did not remain at 5 years. A preoperative BMI ≥ 50 kg/m is the main predictive factor of poor weight outcomes.

摘要

简介

袖状胃切除术(SG)后的胃容量(VGR)会影响短期减重效果,但长期结果较为缺乏。本研究旨在分析 VGR 与术后 5 年随访期间减重效果之间的相关性。

方法

这是一项前瞻性观察研究,纳入了 2009 年 2 月至 2013 年 12 月期间行 SG 的 50 例患者。术后 1 个月、1 年和 5 年分别行上消化道造影。采用复合公式估计 VGR。与减重相关的数据包括:术后 1 个月和 1 年及 5 年时的体重指数(BMI)、体重减轻百分比(%EWL)和 BMI 减轻百分比(%EBMIL)。采用单因素和多因素分析确定可能影响长期减重效果的其他因素。

结果

术后 1 年时的 %EWL 为 74.5(63.8-86),而术后 5 年时为 55.5(47-74.3)(p<0.001)。术后 1 个月时的 VGR 为 114.9(90.5-168.3)mL。术后 1 年和 5 年时 VGR 分别增加至 216.7(155.1-278.6)和 367.5(273-560.3)mL(p<0.001)。尽管术后 1 年时 VGR 与 BMI、%EWL 和 %EBMIL 呈显著负相关,但 5 年后这种相关性消失。多因素分析表明,预测术后 5 年减重效果较差的主要因素是术前 BMI≥50kg/m。

结论

VGR 在研究期间逐渐增加。尽管术后 1 年时 VGR 与体重呈负相关,但 5 年后这种相关性不再存在。术前 BMI≥50kg/m 是预测减重效果不佳的主要因素。

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