Sahin Onder Serap, Sahin-Yilmaz Asli, Gergin Tinay Ozgul, Unsal Busra
Umraniye Research and Education Hospital, Department of Otolaryngology, Turkey.
Umraniye Research and Education Hospital, Department of Otolaryngology, Turkey.
Int J Pediatr Otorhinolaryngol. 2020 May;132:109939. doi: 10.1016/j.ijporl.2020.109939. Epub 2020 Feb 8.
Congenital midnasal stenosis (MNS) is an extremely rare disease which may be life threatening, and shows difficulty in diagnosis and management. This case series summarizes superiority of using intranasal mometasone furoate spray (IMS) and continuous positive airway pressure (CPAP) to treat nasal obstruction in neonates with MNS.
This study reviewed six consecutive cases of MNS.
Three patients were treated with IMS and CPAP. Two patients were treated with endoscopic balloon dilatation without stenting, followed by IMS and CPAP due to persisting nasal obstruction after the operation. One patient was treated with endoscopic balloon dilatation without stenting alone.
This study is the first to review the use of CPAP and IMS as an effective therapy for some patients with MNS. It suggests that conservative management with CPAP and IMS may be an alternative therapeutic option to surgery.
先天性中鼻道狭窄（MNS）是一种极其罕见的疾病，可能危及生命，且诊断和治疗困难。本病例系列总结了使用糠酸莫米松鼻喷雾剂（IMS）和持续气道正压通气（CPAP）治疗新生儿MNS所致鼻阻塞的优势。
本研究回顾了连续6例MNS病例。
3例患者接受了IMS和CPAP治疗。2例患者接受了无支架的内镜球囊扩张术，术后因持续性鼻阻塞而接受了IMS和CPAP治疗。1例患者仅接受了无支架的内镜球囊扩张术。
本研究首次回顾了CPAP和IMS作为部分MNS患者有效治疗方法的应用。这表明CPAP和IMS的保守治疗可能是手术的替代治疗选择。
