Cheaney Barry, El Hashemi Mahboub, Obayashi James, Than Khoi D
School of Medicine, Oregon Health & Science University, Portland, OR, United States.
International University of Africa, Khartoum, Sudan.
J Clin Neurosci. 2020 Apr;74:115-119. doi: 10.1016/j.jocn.2020.02.012. Epub 2020 Feb 14.
Bone growth stimulators have been used as an adjunct to spinal fusion surgery in efforts to increase fusion rates.
The authors retrospectively reviewed the medical records of patients who underwent thoracolumbar fusion surgeries by a single surgeon. Patients were then separated into three groups; pulsed electromagnetic field stimulation (PEMF), combined magnetic field stimulation (CMF) or no stimulation (NS), and computed tomography radiographic results at least 1 year after surgery were compared (solid fusion, stable nonunion, and pseudarthrosis).
A total of 60 patients were included; 16 (26.7%) used PEMF, 24 (40.0%) used CMF, and 20 (33.3%) had NS. There were no significant differences in patient demographics. There was no difference in the mean fusion levels (p = 0. 477). Solid fusion was achieved in 11/16 (68.8%) PEMF, 21/24 (87.5%) CMF, and 20/20 (100.0%) NS patients. Stable nonunion was displayed in 2/24 (8.3%) CMF, and zero PEMF and NS patients. There were 5/16 (31.3%) PEMF, 1/24 (4.2%) CMF, and zero NS patients demonstrating radiologic pseudarthrosis. There was a statistically significant difference between PEMF and CMF (p = 0.017) and between PEMF and NS (p = 0.006) groups. No statistical difference was found between CMF and NS (p = 1.000).
This is the first study to compare PEMF and CMF bone growth stimulators in patients with degenerative pathologies who underwent thoracolumbar spinal fusions. Overall, the addition of these bone growth stimulators does not improve fusion outcomes, although CMF appears superior to PEMF.
骨生长刺激器已被用作脊柱融合手术的辅助手段,以提高融合率。
作者回顾性分析了由单一外科医生进行胸腰椎融合手术患者的病历。然后将患者分为三组:脉冲电磁场刺激(PEMF)组、联合磁场刺激(CMF)组或无刺激(NS)组,并比较术后至少1年的计算机断层扫描影像学结果(坚固融合、稳定不融合和假关节形成)。
共纳入60例患者;16例(26.7%)使用PEMF,24例(40.0%)使用CMF,20例(33.3%)接受NS。患者人口统计学特征无显著差异。平均融合节段数无差异(p = 0.477)。11/16例(68.8%)PEMF组、21/24例(87.5%)CMF组和20/20例(100.0%)NS组患者实现了坚固融合。2/24例(8.3%)CMF组患者出现稳定不融合,PEMF组和NS组无此类情况。5/16例(31.3%)PEMF组、1/24例(4.2%)CMF组和0例NS组患者出现影像学假关节形成。PEMF组与CMF组(p = 0.017)以及PEMF组与NS组(p = 0.006)之间存在统计学显著差异。CMF组与NS组之间未发现统计学差异(p = 1.000)。
这是第一项比较PEMF和CMF骨生长刺激器在接受胸腰椎脊柱融合术的退行性病变患者中的研究。总体而言,添加这些骨生长刺激器并不能改善融合效果,尽管CMF似乎优于PEMF。