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[血细胞单采过程中健康献血者血清生化指标的变化]

[Changes in the serum biochemical indicators in healthy blood donors during cytapheresis].

作者信息

Shtereva T, Gekova K, Mikhalev A, Arsov Ts, Dimitrov D

出版信息

Vutr Boles. 1988;27(3):94-6.

PMID:3206910
Abstract

In the serum of 33 healthy donors to whom 72 cytophereses (31 thrombo-, 25 leuko- and 16 leukothrombocytophereses) were performed by a cell separator "Haemonetix 30" the following indices were followed up by SMA before and after the cytophereses: total protein, albumin, calcium, inorganic phosphorus, cholesterol, glucose, urea, uric acid, creatinine: total and conjugated bilirubin and alkaline phosphatase. Several of the donors were followed up dynamically. Immediately following the cytopheresis a transitory decrease of total protein, albumin, inorganic phosphorus and cholesterol was found. At the following cytopheresis of the same donor (the time interval between two cytophereses varied from 72 hours up to several months) the levels of the total protein, albumin, calcium, inorganic phosphorus and cholesterol had reached their normal values. The glucose level increased transitory though in the reference ranges.

摘要

在使用“Haemonetix 30”细胞分离器对33名健康供者进行了72次血细胞分离术(31次血小板分离术、25次白细胞分离术和16次白细胞血小板分离术)后,通过SMA在血细胞分离术前和术后对以下指标进行了跟踪:总蛋白、白蛋白、钙、无机磷、胆固醇、葡萄糖、尿素、尿酸、肌酐、总胆红素和结合胆红素以及碱性磷酸酶。对部分供者进行了动态跟踪。血细胞分离术后立即发现总蛋白、白蛋白、无机磷和胆固醇出现短暂下降。在同一供者的下一次血细胞分离术时(两次血细胞分离术的时间间隔从72小时到数月不等),总蛋白、白蛋白、钙、无机磷和胆固醇水平已恢复到正常范围。葡萄糖水平虽在参考范围内但出现短暂升高。

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