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儿科肥胖管理趋势,儿科内分泌学会肥胖委员会的一项调查。

Trends in pediatric obesity management, a survey from the Pediatric Endocrine Society Obesity Committee.

机构信息

Vanderbilt University Medical Center, Nashville, TN, USA.

National Institute of Diabetes, Digestive, and Kidney Diseases, National Institutes of Health, Bethesda, MD, USA.

出版信息

J Pediatr Endocrinol Metab. 2020 Apr 28;33(4):469-472. doi: 10.1515/jpem-2019-0546.

Abstract

Background In the United States, 18.5% of children are obese. Dietary and lifestyle modifications are key, but often ineffective. There are limited approved pediatric pharmacotherapies. The objective of this study was to evaluate current treatment practices for pediatric obesity among members of the Pediatric Endocrine Society (PES, n = 1300) and the Pediatric Obesity Weight Evaluation Registry (POWER, n = 42) consortium. Methods A 10-question online survey on treatment of children with obesity in clinical practice was conducted. Results The response rates were 19% for PES and 20% for POWER members. The majority were female (65%) and board certified in pediatric endocrinology (81%). Most practitioners saw 5-10 patients with obesity/week and 19% prescribed weight-loss medications. POWER participants were more likely to prescribe weight-loss medications than PES participants (46% vs. 18%, p =  0.02). Metformin was the most commonly prescribed medication. Response to medication was poor. Use of dietary non-pharmacological treatment options was uncommon. Over half of the respondents (56%) referred patients for bariatric surgery and 53% had local access to pediatric bariatric surgery. Conclusions Metformin was the most common drug prescribed among respondents, but successful weight-loss responses were uncommon. Among practitioners who are using pharmacological interventions, therapeutic strategies vary widely. Targeted research in pharmacologic and surgical treatment for pediatric obesity is urgently needed.

摘要

背景

在美国,有 18.5%的儿童肥胖。饮食和生活方式的改变是关键,但往往效果不佳。经过批准的儿科药物治疗方法有限。本研究的目的是评估儿科内分泌学会(PES,n=1300)和儿科肥胖体重评估登记处(POWER,n=42)成员中儿科肥胖的当前治疗实践。

方法

对临床实践中治疗肥胖儿童的治疗方法进行了 10 个问题的在线调查。

结果

PES 的回复率为 19%,POWER 的回复率为 20%。大多数为女性(65%),小儿内分泌学认证(81%)。大多数医生每周看 5-10 个肥胖患者,19%的医生开减肥药。POWER 参与者比 PES 参与者更有可能开减肥药(46%比 18%,p=0.02)。二甲双胍是最常开的药物。药物治疗效果不佳。饮食非药物治疗方法的应用并不常见。超过一半的受访者(56%)将患者转介给减重手术,53%的人可以获得当地的儿科减重手术。

结论

二甲双胍是受访者中最常开的药物,但减肥效果不常见。在使用药物治疗的医生中,治疗策略差异很大。迫切需要针对儿科肥胖症的药物和手术治疗进行针对性研究。

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